Infectious bursal disease (IBD) is an acute, highly contagious, and immunosuppressive
avian disease caused by IBD virus (IBDV). IBDV VP3 is a multifunctional protein playing a …

ABSTRACT I nfectious b ursal d isease v irus (IBDV) is the archetypal member of the family
Birnaviridae and the etiological agent of Gumboro disease, a highly contagious …

IBDV is economically important to the poultry industry. Very virulent (vv) strains cause higher
mortality rates than other strains for reasons that remain poorly understood. In order to …

SUMOylation is a reversible posttranslational modification involved in the regulation of
diverse biological processes. Growing evidence suggests that virus infection can interfere …

Type I interferon (IFN) response is the first line of host-based innate immune defense against
viral infections. However, viruses have developed multiple strategies to counter host IFN …

Infectious bursal disease virus (IBDV) of the Birnaviridae family leads to immunosuppression
of young chickens by destroying B cells in the bursa of Fabricius (BFs). Given the increasing …

Infectious pancreatic necrosis virus (IPNV) and infectious hematopoietic necrosis virus
(IHNV) are two common viral pathogens that cause severe economic losses in all salmonid …

Abstract Infectious Pancreatic Necrosis Virus (IPNV) is a member of the family Birnaviridae
which causes significant losses in the aquaculture industry. To develop a recombinant …

VP3 protein is a structural protein which plays important roles in the virus assembly and the
inhibition of antiviral innate immunity of infectious bursal disease virus (IBDV). To explore …

Immune dysfunction can be either at the humoral or cellular levels and is mediated by a
myriad of factors including virus-induced immunosuppression. Infectious bursal disease …