MYC is a master transcriptional regulator that controls almost all cellular processes. Over the
last several decades, researchers have strived to define the context-dependent …

Pin1 is the only known peptidyl-prolyl cis–trans isomerase (PPIase) that specifically
recognizes and isomerizes the phosphorylated Serine/Threonine-Proline (pSer/Thr-Pro) …

Arsenic trioxide (ATO) and all-trans retinoic acid (ATRA) combination safely cures fatal acute
promyelocytic leukemia, but their mechanisms of action and efficacy are not fully …

In an attempt to attain synergistic therapeutic benefits and address various intrinsic
limitations of the highly efficient black phosphorus quantum dots (BPQDs), we fabricated …

Hepatocellular carcinoma (HCC) possesses high mortality rate and becomes the third most
common cause of cancer death. Searching new therapeutic strategies for HCC are still …

All-Trans Retinoic Acid (ATRA) is the most active metabolite of vitamin A. It is critically
involved in the regulation of multiple processes, such as cell differentiation and apoptosis …

The liver is an important organ in the human body and performs many functions, such as
digestion, detoxification, metabolism, immune responses, and vitamin and mineral storage …

Ethnopharmacological relevance Qi deficiency liver cancer (QDLC) is an important part of
liver cancer research in traditional Chinese medicine (TCM). In the course of its treatment …

Background Effective methods to deliver therapeutic genes to solid tumors and improve their
bioavailability are the main challenges of current medical research on gene therapy. The …

In recent years, the supercritical fluid (SCF) technology has attracted enormous interest from
researchers over the traditional pharmaceutical manufacturing strategies due to the …