[HTML][HTML] A comprehensive summary of the knowledge on COVID-19 treatment
Currently, the world is challenged by the coronavirus disease 2019 (COVID-19) pandemic.
Epidemiologists and researchers worldwide are invariably trying to understand and combat …
Epidemiologists and researchers worldwide are invariably trying to understand and combat …
[HTML][HTML] In silico evaluation of potential inhibitory activity of remdesivir, favipiravir, ribavirin and galidesivir active forms on SARS-CoV-2 RNA polymerase
Since the outbreak emerged in November 2019, no effective drug has yet been found
against SARS-CoV-2. Repositioning studies of existing drug molecules or candidates are …
against SARS-CoV-2. Repositioning studies of existing drug molecules or candidates are …
[HTML][HTML] Phytochemicals as potential inhibitors for COVID-19 revealed by molecular docking, molecular dynamic simulation and DFT studies
V Puthanveedu, K Muraleedharan - Structural Chemistry, 2022 - Springer
The COVID-19 pandemic outbreak demands the designing of potential drugs as there is no
specific treatment available. Thanks to their safety and effectiveness, phytochemicals have …
specific treatment available. Thanks to their safety and effectiveness, phytochemicals have …
Plant-Derived Natural Non-Nucleoside Analog Inhibitors (NNAIs) against RNA-Dependent RNA Polymerase Complex (nsp7/nsp8/nsp12) of SARS-CoV-2
SAG Naidu, G Mustafa, RA Clemens… - Journal of Dietary …, 2023 - Taylor & Francis
The emergence of fast-spreading SARS-CoV-2 mutants has sparked a new phase of COVID-
19 pandemic. There is a dire necessity for antivirals targeting highly conserved genomic …
19 pandemic. There is a dire necessity for antivirals targeting highly conserved genomic …
In silico evidence of beauvericin antiviral activity against SARS-CoV-2
Background Scientists are still battling severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), the virus responsible for the coronavirus 2019 (COVID-19) pandemic so …
(SARS-CoV-2), the virus responsible for the coronavirus 2019 (COVID-19) pandemic so …
An in-silico study on selected organosulfur compounds as potential drugs for SARS-CoV-2 infection via binding multiple drug targets
The emerging paradigm shift from 'one molecule, one target, for one disease'towards 'multi-
targeted small molecules' has paved an ingenious pathway in drug discovery in recent …
targeted small molecules' has paved an ingenious pathway in drug discovery in recent …
[HTML][HTML] COVID-19 signalome: Potential therapeutic interventions
K Lundstrom, A Hromić-Jahjefendić, E Bilajac… - Cellular signalling, 2023 - Elsevier
The COVID-19 pandemic has triggered intensive research and development of drugs and
vaccines against SARS-CoV-2 during the last two years. The major success was especially …
vaccines against SARS-CoV-2 during the last two years. The major success was especially …
A review on the interaction of nucleoside analogues with SARS-CoV-2 RNA dependent RNA polymerase
The outbreaks of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) in 2019,
have highlighted the concerns about the lack of potential vaccines or antivirals approved for …
have highlighted the concerns about the lack of potential vaccines or antivirals approved for …
Repositioning therapeutics for SARS-CoV-2: Virtual screening of plant-based anti-HIV compounds as possible inhibitors against COVID-19 viral RdRp
M Murali, HG Gowtham, MA Ansari… - Current …, 2022 - ingentaconnect.com
Background: Coronavirus disease 2019 (COVID-19) has caused a global pandemic with a
high mortality and morbidity rate worldwide. The COVID-19 vaccines that are currently in …
high mortality and morbidity rate worldwide. The COVID-19 vaccines that are currently in …
2′-and 3′-ribose modifications of nucleotide analogues establish the structural basis to inhibit the viral replication of SARS-CoV-2
Inhibition of RNA-dependent RNA polymerase (RdRp) by nucleotide analogues with ribose
modification provides a promising antiviral strategy for the treatment of SARS-CoV-2 …
modification provides a promising antiviral strategy for the treatment of SARS-CoV-2 …