Peptide-based cancer therapy: opportunity and challenge
D Wu, Y Gao, Y Qi, L Chen, Y Ma, Y Li - Cancer letters, 2014 - Elsevier
Cancer is one of the leading causes of death worldwide. Conventional cancer therapies
mainly focus on mass cell killing without high specificity and often cause severe side effects …
mainly focus on mass cell killing without high specificity and often cause severe side effects …
Combinatorial peptide libraries: mining for cell-binding peptides
BP Gray, KC Brown - Chemical reviews, 2014 - ACS Publications
The surface of a cell represents a collection of macromolecules, which provides the cell with
a unique cellular landscape specific to the type and state of the cell. Ligands that …
a unique cellular landscape specific to the type and state of the cell. Ligands that …
Cell targeting peptides as smart ligands for targeting of therapeutic or diagnostic agents: a systematic review
A Mousavizadeh, A Jabbari, M Akrami… - Colloids and Surfaces B …, 2017 - Elsevier
Cell targeting peptides (CTP) are small peptides which have high affinity and specificity to a
cell or tissue targets. They are typically identified by using phage display and chemical …
cell or tissue targets. They are typically identified by using phage display and chemical …
Innovative magnetic nanoparticles for PET/MRI bimodal imaging
Superparamagnetic iron oxide nanoparticles were developed as positron emission
tomography (PET) and magnetic resonance imaging (MRI) bimodal imaging agents. These …
tomography (PET) and magnetic resonance imaging (MRI) bimodal imaging agents. These …
Copper radiopharmaceuticals for theranostic applications
A Ahmedova, B Todorov, N Burdzhiev… - European Journal of …, 2018 - Elsevier
The growing advancement in nuclear medicine challenges researchers from several
different fields to integrate imaging and therapeutic modalities in a theranostic …
different fields to integrate imaging and therapeutic modalities in a theranostic …
Engineering novel and improved biocatalysts by cell surface display
Biocatalysts, especially enzymes, have the ability to catalyze reactions with high product
selectivity, utilize a broad range of substrates, and maintain activity at low temperature and …
selectivity, utilize a broad range of substrates, and maintain activity at low temperature and …
Prodrug-embedded angiogenic vessel-targeting nanoparticle: A positive feedback amplifier in hypoxia-induced chemo-photo therapy
Photodynamic therapy (PDT) induced hypoxia can significantly upregulate the expression of
vascular endothelial growth factor (VEGF) at the tumor-stromal interface, resulting in a …
vascular endothelial growth factor (VEGF) at the tumor-stromal interface, resulting in a …
Vascular targeted chitosan-derived nanoparticles as docetaxel carriers for gastric cancer therapy
E Zhang, R Xing, S Liu, K Li, Y Qin, H Yu, P Li - International journal of …, 2019 - Elsevier
A gastric cancer angiogenesis marker peptide, GX1, is promising to be a desirable ligand for
anti-angiogenesis targeted drug of gastric cancer treatment. In this study, GX1 was utilized to …
anti-angiogenesis targeted drug of gastric cancer treatment. In this study, GX1 was utilized to …
Molecular targeted treatment and drug delivery system for gastric cancer
L Jiang, X Gong, W Liao, N Lv, R Yan - Journal of Cancer Research and …, 2021 - Springer
Gastric cancer is still a major cancer worldwide. The early diagnosis rate of gastric cancer in
most high incidence countries is low. At present, the overall treatment effect of gastric cancer …
most high incidence countries is low. At present, the overall treatment effect of gastric cancer …
Synthesis and Evaluation of 64Cu-Labeled Monomeric and Dimeric NGR Peptides for MicroPET Imaging of CD13 Receptor Expression
K Chen, W Ma, G Li, J Wang, W Yang… - Molecular …, 2013 - ACS Publications
The NGR-containing peptides have been shown to bind specifically to
CD13/aminopeptidase N (APN) receptor, one of the attractive tumor vasculature biomarkers …
CD13/aminopeptidase N (APN) receptor, one of the attractive tumor vasculature biomarkers …