Fertilization is defined as the union of two gametes. During fertilization, sperm and egg fuse
to form a diploid zygote to initiate prenatal development. In mammals, fertilization involves …

Testicular 3β-hydroxysteroid dehydrogenase (HSD3B) is a steroidogenic enzyme,
catalyzing the conversion of 3β-hydroxysteroids into 3-keto-steroids. Two distinct isoforms in …

So far, successful de novo formation of testicular tissue followed by complete
spermatogenesis in vitro has been achieved only in rodents. Our findings reveal that primary …

Background: Worldwide, the population explosion and unintended pregnancies pose
serious health issues. The family planning program is a vital element due to reducing …

Abstract Introduction In the Muslim world, the use and acceptance of long-term and
permanent contraceptives were limited. Our aim was to investigate those limiting factors so …

Organoid systems take advantage of the self-organizing capabilities of cells to create
diverse multi-cellular tissue surrogates that constitute a powerful novel class of biological …

Inspired by cocktails, we designed a medium term (2–20 weeks) male contraceptive
strategy. Through a sequential injection process of four reagents (calcium alginate hydrogel …

The continued and rapid expansion of the Earth's population mandates the need for safe
and effective measures of contraception. While a plethora of options exist for women …

Medicinal plants may prove useful in developing plant-based strategies for regulation of
male fertility. The present review describes the antifertility potential of certain medicinal …

Contraceptive vaccine (CV) is a valuable, non-invasive, and alternative method for
purposeful contraception. Sperm antigens are useful targets for producing CVs due to their …