Adaptations of the human placenta to hypoxia: opportunities for interventions in fetal growth restriction

A Colson, P Sonveaux, F Debiève… - Human reproduction …, 2021 - academic.oup.com
BACKGROUND The placenta is the functional interface between the mother and the fetus
during pregnancy, and a critical determinant of fetal growth and life-long health. In the first …

Animal models of human pregnancy and placentation: alternatives to the mouse

AM Carter - Reproduction, 2020 - rep.bioscientifica.com
The mouse is often criticized as a model for pregnancy research as gestation is short, with
much of organ development completed postnatally. There are also differences in the …

Regulation of maternal–fetal metabolic communication

CE Bowman, Z Arany, MJ Wolfgang - Cellular and molecular life sciences, 2021 - Springer
Pregnancy may be the most nutritionally sensitive stage in the life cycle, and improved
metabolic health during gestation and early postnatal life can reduce the risk of chronic …

Diet‐induced maternal obesity impacts feto‐placental growth and induces sex‐specific alterations in placental morphology, mitochondrial bioenergetics, dynamics …

T Napso, SC Lean, M Lu, EJ Mort… - Acta …, 2022 - Wiley Online Library
Aim The current study investigated the impact of maternal obesity on placental phenotype in
relation to fetal growth and sex. Methods Female C57BL6/J mice were fed either a diet high …

Placental adaptations supporting fetal growth during normal and adverse gestational environments

AN Sferruzzi‐Perri, J Lopez‐Tello… - Experimental …, 2023 - Wiley Online Library
The placenta is vital for mammalian development and a key determinant of life‐long health.
It is the interface between the mother and fetus and is responsible for transporting the …

Developmental programming of the female reproductive system—a review

S Yao, J Lopez-Tello… - Biology of …, 2021 - academic.oup.com
Exposures to adverse conditions in utero can lead to permanent changes in the structure
and function of key physiological systems in the developing fetus, increasing the risk of …

State-of-the-art and prospective of nanotechnologies for smart reproductive management of farm animals

NM Hashem, A Gonzalez-Bulnes - Animals, 2020 - mdpi.com
Simple Summary The present review aims to introduce current knowledge and prospective
applications of nanotechnology for improving some of major applied assisted reproductive …

Molecular mechanisms governing offspring metabolic programming in rodent models of in utero stress

ER Christoforou, AN Sferruzzi-Perri - Cellular and Molecular Life Sciences, 2020 - Springer
The results of different human epidemiological datasets provided the impetus to introduce
the now commonly accepted theory coined as 'developmental programming', whereby the …

Reliability of rodent and rabbit models in preeclampsia research

A Sakowicz, M Bralewska, P Kamola… - International Journal of …, 2022 - mdpi.com
In vivo studies on the pathology of gestation, including preeclampsia, often use small
mammals such as rabbits or rodents, ie, mice, rats, hamsters, and guinea pigs. The key …

Interventions for placental insufficiency and fetal growth restriction

BN Davenport, RL Wilson, HN Jones - Placenta, 2022 - Elsevier
Pregnancy complications adversely impact both mother and/or fetus throughout the lifespan.
Fetal growth restriction (FGR) occurs when a fetus fails to reach their intrauterine potential …