It is now nearly 5 years since the last of the currently recognised 5-HT receptors was
identified in terms of its cDNA sequence. Over this period, much effort has been directed …

As a result of its presence in various structures of the central nervous system serotonin (5-
HT) plays a role in a great variety of behaviours such as food intake, activity rythms, sexual …

The hippocampus is required for encoding spatial information. Little is known however,
about how different attributes of learning are related to different types of synaptic plasticity …

It is possible that one of the essential functions of sleep is to take out the garbage, as it were,
erasing and “forgetting” information built up throughout the day that would clutter the …

The serotonergic system is implicated in the neurobiological control of learning and memory,
both in healthy individuals and pathological disorders, although the underlying mechanisms …

The study of 5-hydroxytryptamine (5-HT) system has benefited from the identification,
classification and cloning of multiple 5-HT receptors (5-HT1 to 5-HT7). Growing evidence …

Mechanism is at the heart of understanding, and this chapter addresses underlying brain
mechanisms and pathways of cognition and the impact of sleep on these processes …

Serotonin is a monoamine neurotransmitter, which is phylogenetically conserved in a wide
range of species from nematodes to humans. In mammals, age-related changes in serotonin …

Cognitive impairment is a core feature of schizophrenia as deficits are present in the majority
of patients, frequently precede the onset of other positive symptoms, persist even with …

Serotonin 4 receptors (5-HT4Rs) were discovered 15 years ago. They are codedby a very
complex gene (700Kb, 38 exons) which generates eight carboxy-terminalvariants (a, b, c, d …