Prevention of acute exacerbations of COPD: American college of chest physicians and Canadian thoracic society guideline
GJ Criner, J Bourbeau, RL Diekemper, DR Ouellette… - Chest, 2015 - Elsevier
BACKGROUND: COPD is a major cause of morbidity and mortality in the United States as
well as throughout the rest of the world. An exacerbation of COPD (periodic escalations of …
well as throughout the rest of the world. An exacerbation of COPD (periodic escalations of …
[HTML][HTML] Airway remodeling in chronic obstructive pulmonary disease and asthma: the role of matrix metalloproteinase-9
K Grzela, M Litwiniuk, W Zagorska, T Grzela - Archivum immunologiae et …, 2016 - Springer
Chronic obstructive pulmonary disease (COPD) and asthma are both associated with airflow
restriction and progressive remodeling, which affect the respiratory tract. Among various …
restriction and progressive remodeling, which affect the respiratory tract. Among various …
Association of sputum and blood eosinophil concentrations with clinical measures of COPD severity: an analysis of the SPIROMICS cohort
AT Hastie, FJ Martinez, JL Curtis… - The Lancet …, 2017 - thelancet.com
Background Increased concentrations of eosinophils in blood and sputum in chronic
obstructive pulmonary disease (COPD) have been associated with increased frequency of …
obstructive pulmonary disease (COPD) have been associated with increased frequency of …
[HTML][HTML] The roles of blood lipid-metabolism genes in immune infiltration could promote the development of IDD
W Li, Z Ding, H Zhang, Q Shi, D Wang… - Frontiers in cell and …, 2022 - frontiersin.org
Objectives: Intervertebral disc degeneration is a progressive and chronic disease, usually
manifesting as low back pain. This study aimed to screen effective biomarkers for medical …
manifesting as low back pain. This study aimed to screen effective biomarkers for medical …
Early events in the pathogenesis of chronic obstructive pulmonary disease. Smoking-induced reprogramming of airway epithelial basal progenitor cells
R Shaykhiev, RG Crystal - Annals of the American Thoracic Society, 2014 - atsjournals.org
The airway epithelium is the primary site of the earliest pathologic changes induced by
smoking, contributing to the development of chronic obstructive pulmonary disease (COPD) …
smoking, contributing to the development of chronic obstructive pulmonary disease (COPD) …
IL-17A and the promotion of neutrophilia in acute exacerbation of chronic obstructive pulmonary disease
Rationale: Nontypeable Haemophilus influenzae (NTHi) causes acute exacerbation of
chronic obstructive pulmonary disease (AECOPD). IL-17A is central for neutrophilic …
chronic obstructive pulmonary disease (AECOPD). IL-17A is central for neutrophilic …
[HTML][HTML] Extracellular Hsp70 induces inflammation and modulates LPS/LTA-stimulated inflammatory response in THP-1 cells
Abstract Extracellular Hsp70 (eHsp70) can act as damage-associated molecular pattern
(DAMP) via Toll-like receptors TLR2 and TLR4, and stimulate immune and inflammatory …
(DAMP) via Toll-like receptors TLR2 and TLR4, and stimulate immune and inflammatory …
Metabolomic profiling of asthma and chronic obstructive pulmonary disease: a pilot study differentiating diseases
Background Differentiating asthma from other causes of chronic airflow limitation, such as
chronic obstructive pulmonary disease (COPD), can be difficult in a typical outpatient setting …
chronic obstructive pulmonary disease (COPD), can be difficult in a typical outpatient setting …
[HTML][HTML] Respiratory syncytial virus can infect basal cells and alter human airway epithelial differentiation
Respiratory syncytial virus (RSV) is a major cause of morbidity and mortality worldwide,
causing severe respiratory illness in infants and immune compromised patients. The ciliated …
causing severe respiratory illness in infants and immune compromised patients. The ciliated …
[HTML][HTML] Identification of inflammation-related biomarker Lp-PLA2 for patients with COPD by comprehensive analysis
M Deng, Y Yin, Q Zhang, X Zhou, G Hou - Frontiers in immunology, 2021 - frontiersin.org
Purpose Chronic obstructive pulmonary disease (COPD) is a complex and persistent lung
disease and lack of biomarkers. The aim of this study is to screen and verify effective …
disease and lack of biomarkers. The aim of this study is to screen and verify effective …