BACKGROUND: COPD is a major cause of morbidity and mortality in the United States as
well as throughout the rest of the world. An exacerbation of COPD (periodic escalations of …

Chronic obstructive pulmonary disease (COPD) and asthma are both associated with airflow
restriction and progressive remodeling, which affect the respiratory tract. Among various …

Background Increased concentrations of eosinophils in blood and sputum in chronic
obstructive pulmonary disease (COPD) have been associated with increased frequency of …

Objectives: Intervertebral disc degeneration is a progressive and chronic disease, usually
manifesting as low back pain. This study aimed to screen effective biomarkers for medical …

The airway epithelium is the primary site of the earliest pathologic changes induced by
smoking, contributing to the development of chronic obstructive pulmonary disease (COPD) …

Rationale: Nontypeable Haemophilus influenzae (NTHi) causes acute exacerbation of
chronic obstructive pulmonary disease (AECOPD). IL-17A is central for neutrophilic …

Abstract Extracellular Hsp70 (eHsp70) can act as damage-associated molecular pattern
(DAMP) via Toll-like receptors TLR2 and TLR4, and stimulate immune and inflammatory …

Background Differentiating asthma from other causes of chronic airflow limitation, such as
chronic obstructive pulmonary disease (COPD), can be difficult in a typical outpatient setting …

Respiratory syncytial virus (RSV) is a major cause of morbidity and mortality worldwide,
causing severe respiratory illness in infants and immune compromised patients. The ciliated …

Purpose Chronic obstructive pulmonary disease (COPD) is a complex and persistent lung
disease and lack of biomarkers. The aim of this study is to screen and verify effective …