Penicillium expansum is a necrotrophic plant pathogen with a wide range of fruit hosts. It
causes blue mold rot during fruit storage, transport, and sale, resulting in huge economic …

CRISPR-Cas9 technologies are revolutionizing fungal gene editing. Here we show that
survival of specific Cas9/sgRNA mediated DNA double strand breaks (DSBs) depends on …

Covering: up to 2019 Fungi produce a remarkable diversity of secondary metabolites: small,
bioactive molecules not required for growth but which are essential to their ecological …

Natural products from fungi represent an important source of biologically active metabolites
notably for therapeutic agent development. Genome sequencing revealed that the number …

Fungal secondary metabolites are defined by bioactive properties that ensure adaptation of
the fungus to its environment. Although some of these natural products are promising …

Natural products research increasingly applies-omics technologies to guide molecular
discovery. While the combined analysis of genomic and metabolomic datasets has proved …

Griseofulvin is an antifungal polyketide metabolite produced mainly by ascomycetes. Since it
was commercially introduced in 1959, griseofulvin has been used in treating dermatophyte …

Abstract The Hypoxylaceae (Xylariales, Ascomycota) is a diverse family of mainly
saprotrophic fungi, which commonly occur in angiosperm-dominated forests around the …

Filamentous fungi are highly productive cell factories, often used in industry for the
production of enzymes and small bioactive compounds. Recent years have seen an …

The question of how phenotypic and genomic complexity are inter‐related and how they are
shaped through evolution is a central question in biology that historically has been …