A Robust Phylogenomic Time Tree for Biotechnologically and Medically Important Fungi in the Genera Aspergillus and Penicillium
The filamentous fungal family Aspergillaceae contains> 1,000 known species, mostly in the
genera Aspergillus and Penicillium. Several species are used in the food, biotechnology …
genera Aspergillus and Penicillium. Several species are used in the food, biotechnology …
[HTML][HTML] Penicillium chrysogenum, a Vintage Model with a Cutting-Edge Profile in Biotechnology
The discovery of penicillin entailed a decisive breakthrough in medicine. No other medical
advance has ever had the same impact in the clinical practise. The fungus Penicillium …
advance has ever had the same impact in the clinical practise. The fungus Penicillium …
Dissection of patulin biosynthesis, spatial control and regulation mechanism in Penicillium expansum
B Li, Y Chen, Y Zong, Y Shang, Z Zhang… - Environmental …, 2019 - Wiley Online Library
The patulin biosynthesis is one of model pathways in an understanding of secondary
metabolite biology and network novelties in fungi. However, molecular regulation …
metabolite biology and network novelties in fungi. However, molecular regulation …
Strategies for terpenoid overproduction and new terpenoid discovery
Highlights•In vitro reconstitution of mevalonate pathway provides key information for
terpenoid overproduction.•Microbial host and pathway engineering for terpenoid …
terpenoid overproduction.•Microbial host and pathway engineering for terpenoid …
[HTML][HTML] Engineering of the Filamentous Fungus Penicillium chrysogenum as Cell Factory for Natural Products
F Guzmán-Chávez, RD Zwahlen… - Frontiers in …, 2018 - frontiersin.org
Penicillium chrysogenum (renamed P. rubens) is the most studied member of a family of
more than 350 Penicillium species that constitute the genus. Since the discovery of penicillin …
more than 350 Penicillium species that constitute the genus. Since the discovery of penicillin …
Comparative transcriptomics as a guide to natural product discovery and biosynthetic gene cluster functionality
Bacterial natural products remain an important source of new medicines. DNA sequencing
has revealed that a majority of natural product biosynthetic gene clusters (BGCs) maintained …
has revealed that a majority of natural product biosynthetic gene clusters (BGCs) maintained …
Impact of environmental factors on ochratoxin A: From natural occurrence to control strategy
Ochratoxin A (OTA) contamination and the associated issues of food security, food safety
and economic loss are widespread throughout the world. The occurrence of OTA depends …
and economic loss are widespread throughout the world. The occurrence of OTA depends …
A bacterial-like Pictet–Spenglerase drives the evolution of fungi to produce β-carboline glycosides together with separate genes
Diverse β-carboline (βC) alkaloids are produced by microbes, plants, and animals with
myriad bioactivities and drug potentials. However, the biosynthetic mechanism of βCs …
myriad bioactivities and drug potentials. However, the biosynthetic mechanism of βCs …
[HTML][HTML] High-throughput screening of natural product and synthetic molecule libraries for antibacterial drug discovery
NJ Ayon - Metabolites, 2023 - mdpi.com
Due to the continued emergence of resistance and a lack of new and promising antibiotics,
bacterial infection has become a major public threat. High-throughput screening (HTS) …
bacterial infection has become a major public threat. High-throughput screening (HTS) …
[HTML][HTML] New Penicillium and Talaromyces species from honey, pollen and nests of stingless bees
RN Barbosa, JDP Bezerra, CM Souza-Motta… - Antonie van …, 2018 - Springer
Penicillium and Talaromyces species have a worldwide distribution and are isolated from
various materials and hosts, including insects and their substrates. The aim of this study was …
various materials and hosts, including insects and their substrates. The aim of this study was …