Comparative Genomics Analyses of Lifestyle Transitions at the Origin of an Invasive Fungal Pathogen in the Genus Cryphonectria
L Stauber, S Prospero, D Croll - Msphere, 2020 - Am Soc Microbiol
Emerging fungal pathogens are a threat to forest and agroecosystems, as well as animal
and human health. How pathogens evolve from nonpathogenic ancestors is still poorly …
and human health. How pathogens evolve from nonpathogenic ancestors is still poorly …
Hybrid Transcription Factor Engineering Activates the Silent Secondary Metabolite Gene Cluster for (+)-Asperlin in Aspergillus nidulans
Fungi are a major source of valuable bioactive secondary metabolites (SMs). These
compounds are synthesized by enzymes encoded by genes that are clustered in the …
compounds are synthesized by enzymes encoded by genes that are clustered in the …
Genomic and Chemical Investigation of Bioactive Secondary Metabolites From a Marine-Derived Fungus Penicillium steckii P2648
G Yao, X Chen, H Zheng, D Liao, Z Yu… - Frontiers in …, 2021 - frontiersin.org
Marine fungi of the genus Penicillium are rich resources of secondary metabolites, showing
a variety of biological activities. Our anti-bacterial screening revealed that the crude extract …
a variety of biological activities. Our anti-bacterial screening revealed that the crude extract …
Impact of veA on the development, aggressiveness, dissemination and secondary metabolism of Penicillium expansum
C El Hajj Assaf, SP Snini, S Tadrist… - Molecular Plant …, 2018 - Wiley Online Library
Penicillium expansum, the causal agent of blue mould disease, produces the mycotoxins
patulin and citrinin amongst other secondary metabolites. Secondary metabolism is …
patulin and citrinin amongst other secondary metabolites. Secondary metabolism is …
FunOrder: A robust and semi-automated method for the identification of essential biosynthetic genes through computational molecular co-evolution
GA Vignolle, D Schaffer, L Zehetner… - PLoS computational …, 2021 - journals.plos.org
Secondary metabolites (SMs) are a vast group of compounds with different structures and
properties that have been utilized as drugs, food additives, dyes, and as monomers for novel …
properties that have been utilized as drugs, food additives, dyes, and as monomers for novel …
Comparative genomics of Alexander Fleming's original Penicillium isolate (IMI 15378) reveals sequence divergence of penicillin synthesis genes
Antibiotics were derived originally from wild organisms and therefore understanding how
these compounds evolve among different lineages might help with the design of new …
these compounds evolve among different lineages might help with the design of new …
Biosynthetic Gene Content of the 'Perfume Lichens' Evernia prunastri and Pseudevernia furfuracea
Lichen-forming fungi produce a vast number of unique natural products with a wide variety
of biological activities and human uses. Although lichens have remarkable potential in …
of biological activities and human uses. Although lichens have remarkable potential in …
Physiological characterization of secondary metabolite producing Penicillium cell factories
Background Penicillium species are important producers of bioactive secondary
metabolites. However, the immense diversity of the fungal kingdom is only scarcely …
metabolites. However, the immense diversity of the fungal kingdom is only scarcely …
CYP51 paralogue structure is associated with intrinsic azole resistance in fungi
Azoles are the most commonly used clinical antifungal therapy and also play an important
role in control of plant pathogens. Intrinsic resistance to the azole class of fungicides, which …
role in control of plant pathogens. Intrinsic resistance to the azole class of fungicides, which …
Combination of isotope labeling and molecular networking of tandem mass spectrometry data to reveal 69 unknown metabolites produced by Penicillium nordicum
T Hautbergue, EL Jamin, R Costantino… - Analytical …, 2019 - ACS Publications
The secondary metabolome of Penicillium nordicum is poorly documented despite its
frequent detection on contaminated food and its capacity to produce toxic metabolites such …
frequent detection on contaminated food and its capacity to produce toxic metabolites such …