Intracranial atherosclerotic stenosis: risk factors, diagnosis, and treatment
Intracranial atherosclerotic stenosis (ICAS) is one of the most frequent causes of stroke
worldwide and confers one of the greatest risks of recurrent stroke compared with other …
worldwide and confers one of the greatest risks of recurrent stroke compared with other …
Antithrombotic Therapy for Primary and Secondary Prevention of Ischemic Stroke: JACC State-of-the-Art Review
A Greco, G Occhipinti, D Giacoppo, F Agnello… - Journal of the American …, 2023 - jacc.org
Stroke is a devastating condition with significant morbidity and mortality worldwide.
Antithrombotic therapy plays a crucial role in both primary and secondary prevention of …
Antithrombotic therapy plays a crucial role in both primary and secondary prevention of …
[HTML][HTML] Ticagrelor versus Clopidogrel in CYP2C19 Loss-of-Function Carriers with Stroke or TIA
Background Comparisons between ticagrelor and clopidogrel for the secondary prevention
of stroke in CYP2C19 loss-of-function carriers have not been extensively performed …
of stroke in CYP2C19 loss-of-function carriers have not been extensively performed …
[HTML][HTML] Ticagrelor and aspirin or aspirin alone in acute ischemic stroke or TIA
SC Johnston, P Amarenco, H Denison… - … England Journal of …, 2020 - Mass Medical Soc
Background Trials have evaluated the use of clopidogrel and aspirin to prevent stroke after
an ischemic stroke or transient ischemic attack (TIA). In a previous trial, ticagrelor was not …
an ischemic stroke or transient ischemic attack (TIA). In a previous trial, ticagrelor was not …
[HTML][HTML] Ticagrelor added to aspirin in acute nonsevere ischemic stroke or transient ischemic attack of atherosclerotic origin
P Amarenco, H Denison, SR Evans, A Himmelmann… - Stroke, 2020 - journals.lww.com
Background and Purpose: Among patients with a transient ischemic attack or minor ischemic
strokes, those with ipsilateral atherosclerotic stenosis of cervicocranial vasculature have the …
strokes, those with ipsilateral atherosclerotic stenosis of cervicocranial vasculature have the …
Antiplatelet therapy in cardiovascular disease: Current status and future directions
G Passacquale, P Sharma, D Perera… - British Journal of …, 2022 - Wiley Online Library
Antiplatelet medications remain a cornerstone of therapy for atherosclerotic cardiovascular
and cerebrovascular diseases. In primary prevention (patients with cardiovascular risk …
and cerebrovascular diseases. In primary prevention (patients with cardiovascular risk …
Sex disparities in enrollment in recent randomized clinical trials of acute stroke: a meta-analysis
B Strong, J Pudar, AG Thrift, VJ Howard… - JAMA …, 2021 - jamanetwork.com
Importance The underenrollment of women in randomized clinical trials represents a threat
to the validity of the evidence supporting clinical guidelines and potential disparities in …
to the validity of the evidence supporting clinical guidelines and potential disparities in …
Comparison of ticagrelor vs clopidogrel in addition to aspirin in patients with minor ischemic stroke and transient ischemic attack: a network meta-analysis
Importance Dual antiplatelet therapy (DAPT) with clopidogrel and aspirin is effective in
preventing recurrent strokes after minor ischemic stroke or transient ischemic attack (TIA) …
preventing recurrent strokes after minor ischemic stroke or transient ischemic attack (TIA) …
Pretreatment of indobufen and aspirin and their combinations with clopidogrel or ticagrelor alleviates inflammasome mediated pyroptosis via inhibiting NF-κB/NLRP3 …
F Li, D Xu, K Hou, X Gou, N Lv, W Fang, Y Li - Journal of Neuroimmune …, 2021 - Springer
Increasing studies showed that several anti-platelet drugs turned out to be a promising
strategy for inflammatory response. In this study, we investigated the protective efficiency of …
strategy for inflammatory response. In this study, we investigated the protective efficiency of …
Contemporary antiplatelet and anticoagulant therapies for secondary stroke prevention: a narrative review of current literature and guidelines
K Bhatia, LM Ladd, KH Carr, M Di Napoli… - Current Neurology and …, 2023 - Springer
Abstract Purpose of Review Stroke is a leading cause of death and disability worldwide. The
annual incidence of new or recurrent stroke is approximately 795,000 cases per year in the …
annual incidence of new or recurrent stroke is approximately 795,000 cases per year in the …