Nanoparticle drug delivery systems have proved anti-tumor effects; however, they are not
widely used in tumor therapy due to insufficient ability to target specific sites, multidrug …

Research of nanoscale nucleic acid carriers has garnered attention in recent years due to
their distinctive and controllable properties. However, current knowledge is limited in how …

Polycystic kidney disease (PKD) is a significant cause of end-stage kidney failure and there
are few effective drugs for treating this inherited condition. Numerous aberrantly expressed …

Abstract NLRP3 (NOD-, LRR-and pyrin domain-containing protein 3), a member of the
nucleotide-binding domain (NOD) and leucine-rich repeat sequence (LRR) protein (NLR) …

Recently, nucleic acid drugs have been considered as promising candidates in treatment of
various diseases, especially cancer. Because of developing resistance to conventional …

The successful employment of messenger RNA (mRNA) as vaccine therapy for the
prevention of COVID-19 infection has spotlighted the attention of scientific community onto …

The kidney plays a crucial role in regulating homeostasis within the human body. Renal cell
carcinoma (RCC) is the most common form of kidney cancer, accounting for nearly 90% of …

Renal disorders pose a global health threat, with targeted drug-delivery systems emerging
as a promising strategy to enhance therapy safety and efficacy. Recent efforts have …

Abstract The 14th International Podocyte Conference took place in Philadelphia, USA, from
May 23rd to 26th, 2023. It commenced with an early-career researchers' meeting on May …

Small molecules and biologics are the two major categories of active pharmaceutical
ingredients (APIs) commonly used for disease management. Lipid-based nanocarriers have …