[HTML][HTML] Advanced surface engineering of titanium materials for biomedical applications: From static modification to dynamic responsive regulation

P Jiang, Y Zhang, R Hu, B Shi, L Zhang, Q Huang… - Bioactive Materials, 2023 - Elsevier
Titanium (Ti) and its alloys have been widely used as orthopedic implants, because of their
favorable mechanical properties, corrosion resistance and biocompatibility. Despite their …

Flowerbed-inspired biomimetic scaffold with rapid internal tissue infiltration and vascularization capacity for bone repair

X Zhou, Y Qian, L Chen, T Li, X Sun, X Ma, J Wang… - ACS …, 2023 - ACS Publications
The favorable microstructure and bioactivity of tissue-engineered bone scaffolds are closely
associated with the regenerative efficacy of bone defects. For the treatment of large bone …

Engineered extracellular vesicles in wound healing: design, paradigms, and clinical application

Y Liao, Z Zhang, L Ouyang, B Mi, G Liu - Small, 2024 - Wiley Online Library
The severe quality of life and economic burden imposed by non‐healing skin wounds,
infection risks, and treatment costs are affecting millions of patients worldwide. To mitigate …

Mild photothermal‐stimulation based on injectable and photocurable hydrogels orchestrates immunomodulation and osteogenesis for high‐performance bone …

M Wu, H Liu, Y Zhu, F Chen, Z Chen, L Guo, P Wu, G Li… - Small, 2023 - Wiley Online Library
A photoactivated bone scaffold integrated with minimally invasive implantation and mild
thermal‐stimulation capability shows great promise in the repair and regeneration of …

Bioinspired piezoelectric periosteum to augment bone regeneration via synergistic immunomodulation and osteogenesis

H Liu, Y Shi, Y Zhu, P Wu, Z Deng, Q Dong… - … Applied Materials & …, 2023 - ACS Publications
Ideal periosteum materials are required to participate in a sequence of bone repair-related
physiological events, including the initial immune response, endogenous stem cell …

Stem cell membrane‐coated microribbon scaffolds induce regenerative innate and adaptive immune responses in a critical‐size cranial bone defect model

N Su, C Villicana, D Barati, P Freeman… - Advanced …, 2023 - Wiley Online Library
Naturally‐derived cell membranes have shown great promise in functionalizing
nanoparticles to enhance biointerfacing functions for drug delivery applications. However, its …

Spatiotemporal Regulation of the Bone Immune Microenvironment via Dam‐Like Biphasic Bionic Periosteum for Bone Regeneration

Z Xu, L Wu, Y Tang, K Xi, J Tang, Y Xu… - Advanced …, 2023 - Wiley Online Library
The bone immune microenvironment (BIM) regulates bone regeneration and affects the
prognosis of fractures. However, there is currently no effective strategy that can precisely …

Smart‐Responsive Multifunctional Therapeutic System for Improved Regenerative Microenvironment and Accelerated Bone Regeneration via Mild Photothermal …

M Wu, H Liu, D Li, Y Zhu, P Wu, Z Chen… - Advanced …, 2024 - Wiley Online Library
The treatment of bone defects remains a substantial clinical challenge due to the lack of
spatiotemporal management of the immune microenvironment, revascularization, and …

Selenium-Doped Mesoporous Bioactive Glass Regulates Macrophage Metabolism and Polarization by Scavenging ROS and Promotes Bone Regeneration In Vivo

D Chen, Z Liang, Z Su, J Huang, Y Pi… - … Applied Materials & …, 2023 - ACS Publications
Bone regeneration is complex and involves multiple cells and systems, with macrophage-
mediated immune regulation being critical for the development and regulation of …

Janus Membrane with Intrafibrillarly Strontium-Apatite-Mineralized Collagen for Guided Bone Regeneration

Y Zhao, W Sun, X Wu, X Gao, F Song, B Duan, A Lu… - ACS …, 2024 - ACS Publications
Commercial collagen membranes face difficulty in guided bone regeneration (GBR) due to
the absence of hierarchical structural design, effective interface management, and diverse …