[HTML][HTML] Traditional Chinese medicine: role in reducing β-amyloid, apoptosis, autophagy, neuroinflammation, oxidative stress, and mitochondrial dysfunction of …
SY Chen, Y Gao, JY Sun, XL Meng, D Yang… - Frontiers in …, 2020 - frontiersin.org
Alzheimer's disease (AD) is a progressive age-related neurodegenerative disease
characterized by memory loss and cognitive impairment. The major characteristics of AD are …
characterized by memory loss and cognitive impairment. The major characteristics of AD are …
[HTML][HTML] miR-23b-3p rescues cognition in Alzheimer's disease by reducing tau phosphorylation and apoptosis via GSK-3β signaling pathways
H Jiang, J Liu, S Guo, L Zeng, Z Cai, J Zhang… - … Therapy-Nucleic Acids, 2022 - cell.com
Dysregulated microRNA (miRNA) expression in the brain can contribute to cognitive
dysfunction and aberrant tau hyperphosphorylation in Alzheimer's disease (AD). Several …
dysfunction and aberrant tau hyperphosphorylation in Alzheimer's disease (AD). Several …
[HTML][HTML] East wind, west wind: toward the modernization of traditional Chinese medicine
E Yagüe, H Sun, Y Hu - Frontiers in Neuroscience, 2022 - frontiersin.org
Traditional Chinese medicine (TCM) has used herbal remedies for more than 2,000 years.
The use of complimentary therapies has increased dramatically during the last years …
The use of complimentary therapies has increased dramatically during the last years …
miR-30a-5p induces Aβ production via inhibiting the nonamyloidogenic pathway in Alzheimer's disease
T Sun, K Zhao, M Liu, Z Cai, L Zeng, J Zhang… - Pharmacological …, 2022 - Elsevier
Alzheimer's disease (AD) pathogenesis is known to involve a dysregulation of microRNA
expression, and these intricate transcriptional cascades between multiple pathological …
expression, and these intricate transcriptional cascades between multiple pathological …
[HTML][HTML] Tilianin ameliorates cognitive dysfunction and neuronal damage in rats with vascular dementia via p-CaMKII/ERK/CREB and ox-CaMKII-dependent MAPK/NF …
H Jiang, GM Ashraf, M Liu, K Zhao, Y Wang… - … medicine and cellular …, 2021 - hindawi.com
Vascular dementia (VaD) is a common cause of cognitive decline and dementia of vascular
origin, but the precise pathological mechanisms are unknown, and so effective clinical …
origin, but the precise pathological mechanisms are unknown, and so effective clinical …
[HTML][HTML] MicroRNA and mRNA profiling of cerebral cortex in a transgenic mouse model of Alzheimer's disease by RNA sequencing
L Zeng, HL Jiang, GM Ashraf, ZR Li… - Neural regeneration …, 2021 - journals.lww.com
In a previous study, we found that long non-coding genes in Alzheimer's disease (AD) are a
result of endogenous gene disorders caused by the recruitment of microRNA (miRNA) and …
result of endogenous gene disorders caused by the recruitment of microRNA (miRNA) and …
[HTML][HTML] Tilianin improves cognition in a vascular dementia rodent model by targeting miR-193b-3p/CaM-and miR-152-3p/CaMKIIα-mediated inflammatory and …
T Sun, L Tan, M Liu, L Zeng, K Zhao, Z Cai… - Frontiers in …, 2023 - frontiersin.org
Introduction Although vascular dementia (VaD) is the second most prevalent form of
dementia, there is currently a lack of effective treatments. Tilianin, isolated from the …
dementia, there is currently a lack of effective treatments. Tilianin, isolated from the …
[HTML][HTML] RNA sequencing-based identification of the regulatory mechanism of microRNAs, transcription factors, and corresponding target genes involved in vascular …
K Zhao, L Zeng, Z Cai, M Liu, T Sun, Z Li… - Frontiers in …, 2022 - frontiersin.org
Vascular dementia (VaD) is the second most common form of dementia with uncertain
mechanisms and no effective treatments. microRNAs (miRNAs) and transcription factors …
mechanisms and no effective treatments. microRNAs (miRNAs) and transcription factors …
[HTML][HTML] Tilianin Protects against Ischemia/Reperfusion-Induced Myocardial Injury through the Inhibition of the Ca2+/Calmodulin-Dependent Protein Kinase II …
H Jiang, J Xing, J Fang, L Wang, Y Wang… - BioMed Research …, 2020 - hindawi.com
Tilianin is a naturally occurring phenolic compound with a cardioprotective effect against
myocardial ischemia/reperfusion injury (MIRI). The aim of our study was to determine the …
myocardial ischemia/reperfusion injury (MIRI). The aim of our study was to determine the …
Tilianin mediates neuroprotection against ischemic injury by attenuating CaMKII-dependent mitochondrion-mediated apoptosis and MAPK/NF-κB signaling
H Jiang, J Fang, J Xing, L Wang, Q Wang, Y Wang, Z Li… - Life sciences, 2019 - Elsevier
Aims Tilianin, a naturally occurring flavonoid glycoside, possesses versatile biological
activities including antioxidant, anti-inflammatory, energy collecting and anti-hypoxic effects …
activities including antioxidant, anti-inflammatory, energy collecting and anti-hypoxic effects …