The long-term course of cyclosporine-associated chronic nephropathy. We evaluated a
chronic renal injury in 37 cardiac transplant recipients treated for 12 to 24 months with …

The pharmacokinetics of angiotension converting enzyme (ACE) inhibitors enalapril (10 mg
orally) and its active metabolite, enalaprilat (10 mg intravenously) were studied in nine …

Over the last several decades, angiotensin-converting enzyme inhibitors (ACEIs) have been
a staple in the treatment of hypertension and renovascular disorders in children. One of the …

Although only recently introduced, angiotensin-converting enzyme inhibitors have been
utilized to treat a wide variety of clinical disorders. Their uses to date, approved by the Food …

Methods Patients. Within 5 days prior to drug administration, 18 patients with chronic renal
failure were divided into the follow-ing three groups on the basis of a measurement of …

The pharmacokinetic parameters of unchanged plasma captopril and the kinetics of the drug
effects on plasma converting enzyme activity (PCEA), plasma renin activity (PRA), plasma …

A number of side effects have been observed in the use of captopril therapy. Many of these
symptoms are typical of trace element deficiency and it seems probable that this agent …

The effect of acute renal failure (ARF) on the metabolism and covalent binding to plasma
proteins (PP) of [14 C] captopril ([14 C] CP) was investigated in the Wistar rat in vivo and in …

Pharmacokinetics and pharmacodynamics of captopril were studied in 5 continuous
ambulatory peritoneal dialysis (CAPD) patients (including 2 hypertensive patients) after …

We have measured the plasma concentrations of captopril and total disulfide conjugates of
captopril after a 50 mg oral dose in 6 uraemic patients on maintenance dialysis and in 8 …