Glycotargeting therapeutics

JA Hubbell, S Kontos, KM Lorentz, DS Wilson… - US Patent …, 2020 - Google Patents
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Erythrocyte-binding therapeutics

JA Hubbell, S Kontos, KY Dane - US Patent 9,518,087, 2016 - Google Patents
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Needle insertion mechanisms for drug containers

M McCaffrey, I McLaughlin - US Patent 11,045,603, 2021 - Google Patents
Abstract Systems for piercing a septum of a drug delivery device is disclosed. The drug
delivery device may include a needle conduit having an end and a drug container having a …

Erythrocyte-binding therapeutics

JA Hubbell, S Kontos, KY Dane - US Patent 9,517,257, 2016 - Google Patents
Peptides that specifically bind erythrocytes are described. These are provided as peptidic
ligands having sequences that specifically bind, or as antibodies or fragments thereof that …

Isolation and use of solid tumor stem cells

MF Clarke, SJ Morrison, MS Wicha, M Al-Hajj - US Patent 9,492,538, 2016 - Google Patents
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Noninvasive genetic immunization, expression products therefrom, and uses thereof

CT De-chu, DH Marks, DT Curiel, Z Shi - US Patent 6,716,823, 2004 - Google Patents
Disclosed and claimed are methods of non-invasive genetic immunization in an animal
and/or methods of inducing a systemic immune or therapeutic response in an animal …

Vaccination by topical application of recombinant vectors

DC Tang, Z Shi, K Kampen - US Patent App. 10/116,963, 2003 - Google Patents
The present invention relates to techniques of skin-targeted non-invasive gene delivery to
elicit immune responses and uses thereof. The invention further relates to methods of non …

Determining the capability of a test compound to affect solid tumor stem cells

MF Clarke, SJ Dylla, S Satyal - US Patent 8,044,259, 2011 - Google Patents
A small percentage of cells within an established solid tumor have the properties of stem
cells. These solid tumor stem cells give rise both to more tumor stem cells and to the majority …

Compositions for inducing antigen-specific tolerance

JA Hubbell, S Kontos, KY Dane - US Patent 9,814,780, 2017 - Google Patents
US9814780B2 - Compositions for inducing antigen-specific tolerance - Google Patents
US9814780B2 - Compositions for inducing antigen-specific tolerance - Google Patents …

Hepatocyte production via forward programming by combined genetic and chemical engineering

J Yu, X Zhang - 2014 - Google Patents
G01N33/5008—Chemical analysis of biological material, eg blood, urine; Testing involving
biospecific ligand binding methods; Immunological testing involving human or animal cells …