Human frizzled (FZD) receptor polypeptides and methods of use thereof for treating cancer and inhibiting growth of tumor cells

AL Gurney, J Lewicki, S Satyal, T Hoey - US Patent 8,765,913, 2014 - Google Patents
The present invention relates to compositions and methods for characterizing, diagnosing,
and treating cancer. In par ticular the invention provides the means and methods for the …

Modified adenovirus containing a fiber replacement protein

DT Curiel, VN Krasnykh - US Patent 6,210,946, 2001 - Google Patents
The present invention provides means to modify the tropism of recombinant adenoviral
vectors using genetic methods to alter the adenoviral fiber cell-binding protein while …

Multifunctional biomaterials as scaffolds for electronic, optical, magnetic, semiconducting, and biotechnological applications

AM Belcher, BR Peelle, KT Nam - US Patent 8,088,982, 2012 - Google Patents
One-dimensional ring structures from M13 viruses were con structed by two genetic
modifications encoding binding pep tides and synthesis of a heterobifunctional linker …

Virus like particles, their preparation and their use preferably in pharmaceutical screening and functional genomics

N Hunt - US Patent App. 10/322,766, 2004 - Google Patents
US20040014033A1 - Virus like particles, their preparation and their use preferably in
pharmaceutical screening and functional genomics - Google Patents US20040014033A1 - Virus …

Compositions for inducing antigen-specific tolerance

JA Hubbell, S Kontos, KY Dane - US Patent 10,265,415, 2019 - Google Patents
US10265415B2 - Compositions for inducing antigen-specific tolerance - Google Patents
US10265415B2 - Compositions for inducing antigen-specific tolerance - Google Patents …

Dek protein compositions and methods of using the same

DM Markovitz, N Mor-Vaknin, M Khodadoust… - US Patent …, 2014 - Google Patents
The present invention relates to DEK protein compositions (eg, antibodies, Small molecule
inhibitors, siRNAs) and methods of using the same. In particular, the present invention …

Therapeutic ribonucleases

T Klink, J Kink, L Strong - US Patent 8,216,567, 2012 - Google Patents
Protein therapeutics in general may offer particular advantages as alternatives to small
molecules; however, effective protein drugs must have a balance of optimal properties that …

Compositions and methods for ribonuclease-based therapeutics

RT Raines, TJ Rutkoski, JA Kink, LE Strong - US Patent 8,697,062, 2014 - Google Patents
5,270,163 A 12, 1993 Gold t1OnS comprising the conjugates and metho is of using the
5,270,204 A 12, 1993 Vallee same. In particular, the present invention provides conjugates …

Methods and compositions for use in spliceosome mediated RNA trans-splicing

L Mitchell, M Garcia-Blanco, C Baker… - US Patent App. 11 …, 2006 - Google Patents
The molecules and methods of the present invention provide a means for in vivo production
of a trans-spliced molecule in a selected subset of cells. The pre-trans-splicing molecules of …

Screening method for identification of efficient pre-trans-splicing molecules

L Mitchell, M Puttaraju, M Garcia-Blanco… - US Patent App. 10 …, 2006 - Google Patents
The present invention provides methods and compositions for rapid high capacity functional
screening to identify optimal pre-trans-splicing molecules (PTMs). The compo sitions of the …