Functional characterisation of long intergenic non-coding RNAs through genetic interaction profiling in Saccharomyces cerevisiae
D Kyriakou, E Stavrou, P Demosthenous, G Angelidou… - BMC biology, 2016 - Springer
Background Transcriptome studies have revealed that many eukaryotic genomes are
pervasively transcribed producing numerous long non-coding RNAs (lncRNAs). However …
pervasively transcribed producing numerous long non-coding RNAs (lncRNAs). However …
[PDF][PDF] The role of shelterin in maintaining telomere integrity
MP Longhese, S Anbalagan, M Martina, D Bonetti - Front Biosci, 2012 - article.imrpress.com
[Frontiers in Bioscience 17, 1715-1728, January 1, 2012] 1715 The role of shelterin in
maintaining telomere integrity Maria Pia Page 1 [Frontiers in Bioscience 17, 1715-1728 …
maintaining telomere integrity Maria Pia Page 1 [Frontiers in Bioscience 17, 1715-1728 …
Homologous recombination repair intermediates promote efficient de novo telomere addition at DNA double-strand breaks
A Davé, CC Pai, SC Durley, L Hulme… - Nucleic Acids …, 2020 - academic.oup.com
The healing of broken chromosomes by de novo telomere addition, while a normal
developmental process in some organisms, has the potential to cause extensive loss of …
developmental process in some organisms, has the potential to cause extensive loss of …
Sequential phosphorylation of CST subunits by different cyclin-Cdk1 complexes orchestrate telomere replication
V Gopalakrishnan, CR Tan, S Li - Cell Cycle, 2017 - Taylor & Francis
Telomeres are nucleoprotein structures that cap the ends of linear chromosomes. Telomere
homeostasis is central to maintaining genomic integrity. In budding yeast, Cdk1 …
homeostasis is central to maintaining genomic integrity. In budding yeast, Cdk1 …
γH2A is a component of yeast heterochromatin required for telomere elongation
Histones of heterochromatin are deacetylated in yeast and methylated in more complex
eukaryotes to regulate heterochromatin structure and gene silencing. Here, we report that …
eukaryotes to regulate heterochromatin structure and gene silencing. Here, we report that …
Telomerase activity is required for the telomere G-overhang structure in Trypanosoma brucei
Trypanosoma brucei causes fatal human African trypanosomiasis and evades the host
immune response by regularly switching its major surface antigen, VSG, which is expressed …
immune response by regularly switching its major surface antigen, VSG, which is expressed …
Sgs1 helicase is required for efficient PCNA monoubiquitination and translesion DNA synthesis in Saccharomyces cerevisiae
DNA-damage tolerance (DDT) is employed by eukaryotes to deal with replication blocks on
the template strand, and is divided into two parallel pathways that are activated by …
the template strand, and is divided into two parallel pathways that are activated by …
The telomeric 5′ end nucleotide is regulated in the budding yeast Naumovozyma castellii
H Itriago, RK Jaiswal, S Philipp… - Nucleic Acids Research, 2022 - academic.oup.com
The junction between the double-stranded and single-stranded telomeric DNA (ds–ss
junction) is fundamental in the maintenance of the telomeric chromatin, as it directs the …
junction) is fundamental in the maintenance of the telomeric chromatin, as it directs the …
The Mre11-Rad50-Xrs2 complex is required for yeast DNA postreplication repair
LG Ball, MD Hanna, AD Lambrecht, BA Mitchell… - PLoS …, 2014 - journals.plos.org
Yeast DNA postreplication repair (PRR) bypasses replication-blocking lesions to prevent
damage-induced cell death. PRR employs two different mechanisms to bypass damaged …
damage-induced cell death. PRR employs two different mechanisms to bypass damaged …
To trim or not to trim: progression and control of DSB end resection
DNA double-strand breaks (DSBs) are the most cytotoxic form of DNA damage, since they
can lead to genome instability and chromosome rearrangements, which are hallmarks of …
can lead to genome instability and chromosome rearrangements, which are hallmarks of …