Evolution of our understanding of the hyperparathyroid syndromes: a historical perspective

SJ Marx, D Goltzman - Journal of Bone and Mineral Research, 2019 - academic.oup.com
We review advancing and overlapping stages for our understanding of the expressions of
six hyperparathyroid (HPT) syndromes: multiple endocrine neoplasia type 1 (MEN1) or type …

The architecture of clonal expansions in morphologically normal tissue from cancerous and non-cancerous prostates

C Buhigas, AY Warren, WK Leung, HC Whitaker… - Molecular cancer, 2022 - Springer
Background Up to 80% of cases of prostate cancer present with multifocal independent
tumour lesions leading to the concept of a field effect present in the normal prostate …

p53-intact cancers escape tumor suppression through loss of long noncoding RNA Dino

CB Marney, ES Anderson, M Adnan, KL Peng, Y Hu… - Cell reports, 2021 - cell.com
Many long noncoding RNA (lncRNA) genes exist near cancer-associated loci, yet evidence
connecting lncRNA functions to recurrent genetic alterations in cancer are lacking. Here, we …

m6A Methylation-Mediated Stabilization of LINC01106 Suppresses Bladder Cancer Progression by Regulating the miR-3148/DAB1 Axis

J Liu, C Tian, J Qiao, K Deng, X Ye, L Xiong - Biomedicines, 2024 - mdpi.com
Background: The pivotal roles of long noncoding RNAs (lncRNAs) in the realm of cancer
biology, inclusive of bladder cancer (BCa), have been substantiated through various studies …

Upregulation of microRNA-96 and its oncogenic functions by targeting CDKN1A in bladder cancer

Z Wu, K Liu, Y Wang, Z Xu, J Meng, S Gu - Cancer cell international, 2015 - Springer
Background Genome-wide miRNA expression profile has identified microRNA (miR)-96 as
one of upregulated miRNAs in clinical bladder cancer (BC) tissues compared to normal …

Sulforaphane suppresses the viability and metastasis, and promotes the apoptosis of bladder cancer cells by inhibiting the expression of FAT‑1 Corrigendum in …

F Wang, P Liu, H An, Y Zhang - … journal of molecular …, 2020 - spandidos-publications.com
Abstract FAT atypical cadherin 1 (FAT1) regulates complex mechanisms for the promotion of
oncogenesis or the suppression of malignancies. Sulforaphane (SFN) has antioxidant and …

Key signaling pathways in the muscle‐invasive bladder carcinoma: clinical markers for disease modeling and optimized treatment

A Kiselyov… - … Journal of Cancer, 2016 - Wiley Online Library
In this review, we evaluate key molecular pathways and markers of muscle‐invasive bladder
cancer (MIBC). Overexpression and activation of EGFR, p63, and EMT genes are suggestive …

Distribution of copy number variations and rearrangement endpoints in human cancers with a review of literature

G Mirzaei, RC Petreaca - Mutation Research/Fundamental and Molecular …, 2022 - Elsevier
Copy number variations (CNVs) which include deletions, duplications, inversions,
translocations, and other forms of chromosomal re-arrangements are common to human …

Molecular biology of bladder cancer

W Martin-Doyle, DJ Kwiatkowski - Hematology/Oncology …, 2015 - hemonc.theclinics.com
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Low mutation and neoantigen burden and fewer effector tumor infiltrating lymphocytes correlate with breast cancer metastasization to lymph nodes

Z Wang, W Liu, C Chen, X Yang, Y Luo, B Zhang - Scientific Reports, 2019 - nature.com
Lymph node metastasis is of major prognostic significance for breast cancer. Lymph node
metastasis arises at a very early stage in some patients. Using the data downloaded from …