Although liver transplantation is a true success story, many patients still die awaiting an
organ. The increasing need for liver grafts therefore remains an unsolved challenge to the …

The development of cholangiopathies after liver transplantation impacts on the quality and
duration of graft and patient survival, contributing to higher costs as numerous interventions …

Background Transplantation of livers obtained from donors after circulatory death is
associated with an increased risk of nonanastomotic biliary strictures. Hypothermic …

Objective: The aim of this study was to evaluate peak serum alanine aminotransferase (ALT)
and postoperative clinical outcomes after hypothermic oxygenated machine perfusion …

Background Mitochondrial succinate accumulation has been suggested as key event for
ischemia reperfusion injury in mice. No specific data are however available on behavior of …

Objective: The aim of this study was to evaluate sequential hypothermic and normothermic
machine perfusion (NMP) as a tool to resuscitate and assess viability of initially declined …

Ex situ normothermic machine perfusion (NMP) is increasingly used for viability assessment
of high‐risk donor livers, whereas dual hypothermic oxygenated machine perfusion …

The limited preservation duration of organs has contributed to the shortage of organs for
transplantation. Recently, a tripling of the storage duration was achieved with supercooling …

Based on the continuous increase of donor risk, with a majority of organs classified as
marginal, quality assessment and prediction of liver function is of utmost importance. This is …

The transplant community continues to be challenged by the disparity between the need for
liver transplantation and the shortage of suitable donor organs. At the same time, the …