Yeast cell surface display of proteins and uses thereof

KD Wittrup, DM Kranz, M Keike, ET Boder - US Patent 6,423,538, 2002 - Google Patents
The present invention provides a genetic method for teth ering polypeptides to the yeast cell
wall in a form accessible for binding to macromolecules. Combining this method with …

Universal anti-tag chimeric antigen receptor-expressing T cells and methods of treating cancer

E Davila, K Tamada - US Patent 9,233,125, 2016 - Google Patents
The present invention provides a universal, yet adaptable, anti-tag chimeric antigen receptor
(AT-CAR) system which provides T cells with the ability and specificity to recognize and kill …

Peptidic chimeric antigen receptor T cell switches and uses thereof

T Young, C Kim, PG Schultz - US Patent 9,624,276, 2017 - Google Patents
C07K I4/00(2006.01) US Appl. No. 14/432,065, Travis Young. C07K 6/00(2006.01) AXup, J.
et al., Synthesis of site-specific antibody-drug conjugates A6 IK 39/00(2006.01) using …

Use of complement inhibitors to treat ocular diseases

SC Fung, Z Yao - US Patent 8,753,625, 2014 - Google Patents
7,432,356 B2 10/2008 Fung et al. 7,439,331 B2 10/2008 Fung et al. 7,943,135 B2 5/2011
Fung et al. 8,007,791 B2 8, 2011 Hasset al. 8,124,090 B2 2/2012 Fung et al. 8, 193,329 B2 …

J591 minibodies and Cys-diabodies for targeting human prostate specific membrane antigen (PSMA) and methods for their use

D Ho, T Olafsen, A Lipman - US Patent 8,772,459, 2014 - Google Patents
In one embodiment, a minibody monomer that binds PSMA is provided. The minibody
monomer is encoded by a nucle otide sequence comprising, from N-terminus to C-terminus …

Anti-properdin antibodies, and methods for making and using same

G Gazit-Bornstein, G Senaldi, XD Yang, B Keyt… - US Patent …, 2008 - Google Patents
US7423128B2 - Anti-properdin antibodies, and methods for making and using same -
Google Patents US7423128B2 - Anti-properdin antibodies, and methods for making and …

Inhibitors of complement activation

MSC Fung, WNC Sun, CRY Sun - US Patent 6,956,107, 2005 - Google Patents
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Fodor et al. 5,679.546 A 10/1997 Ko et al. 5,851,528. A 12/1998 Ko et al. 5,853,722 A …

Engineered anti-prostate stem cell antigen (PSCA) antibodies for cancer targeting

AM Wu, RE Reiter - US Patent 8,940,871, 2015 - Google Patents
The present invention provides engineered PSCA-specific humanized antibody fragments,
eg, ScPV dimers (diabod ies), sclv-CH3 dimers (minibodies), and scFv-Fc, that have in vivo …

Viral vectors and methods for producing and using the same

A Amalfitano, DD Koeberl, B Sun - US Patent 7,858,367, 2010 - Google Patents
(57) ABSTRACT A recombinant hybrid virus which includes:(a) a deleted adenovirus vector
genome having the adenovirus 5'and 3'cis-elements for viral replication and encapsidation …

Yeast cell surface display of proteins and uses thereof

KD Wittrup, DM Kranz, M Kieke, ET Boder - US Patent 7,465,787, 2008 - Google Patents
Related US Application Data(Continued)(60) Division of application No. 09/724,108, filed on
Nov. FOREIGN PATENT DOCUMENTS 28, 2000, now Pat. No. 6,696,251, which is a continu …