Background and study aims: A recent international guideline recommends surveillance of
premalignant gastric lesions for patients at risk of progression to gastric cancer. The aim of …

BACKGROUND & AIMS: Improving methods for early detection of gastric cancer could
reduce mortality. Measurements of serum pepsinogen levels have been used for screening …

Intestinal metaplasia of the stomach is a preneoplastic lesion that appears following
Helicobacter pylori infection and confers increased risk for gastric cancer development …

Serum pepsinogen (PG) has been used as biomarkers of gastric inflammation and mucosal
status, including atrophic change, before the discovery of Helicobacter pylori (H. pylori) …

Endoscopic evaluation and mucosal biopsy analysis have assumed important roles in the
clinical management of patients with symptoms related to the gastrointestinal tract. Several …

BACKGROUND: Conventional endoscopy has low sensitivity, specificity, and interobserver
agreement for the diagnosis of gastric atrophy, intestinal metaplasia, and dysplasia …

Intestinal metaplasia (IM) of the stomach is a risk factor in developing intestinal-type gastric
cancer and hence the question of reversibility is vital. There is emerging epidemiological …

Helicobacter pylori is a major risk factor for chronic atrophic gastritis (CAG). A large variety of
definitions of CAG have been used in epidemiologic studies in the past. The aim of this work …

Gastric carcinogenesis is a complex, multistep and multifactorial event, characterized by
progressive cyto-histological dedifferentiation, in which the role of Helicobacter pylori …

Background The majority of gastric cancer cases are believed to be caused by chronic
infection with the bacterium Helicobacter pylori, and atrophic corpus gastritis is a …