Gastric carcinogenesis involves the loss of parietal cells (oxyntic atrophy) and subsequent
replacement of the normal gastric lineages with metaplastic cells. In humans, two …

BACKGROUND AND STUDY AIMS: Intestinal metaplasia, especially type III intestinal
metaplasia is considered to be a precursor of gastric cancer and because of this it is …

Background & Aims: Increase of intramucosal transforming growth factor α (TGFα) levels in
the gastric fundus leads to oxyntic atrophy and massive foveolar hyperplasia in both …

Objective The aim of this study was the evaluation of the diagnostic accuracy of a specific
high-definition white light endoscopy (HD-WLE) system for the optical recognition of …

Helicobacter pylori colonization of the human stomach is a strong risk factor for gastric
cancer. To investigate H. pylori-induced gastric molecular alterations, we used a Mongolian …

Background and Aims The prevalence of precursor lesions for gastric cancer (GC) and the
differential burden between countries of varying GC risk is not well understood. We …

Background. Oxidative DNA damage is associated with Helicobacter pylori infection, atrophy
and intestinal metaplasia. H. pylori‐cagA‐positive strains are associated with the highest …

Gastric cancer ranks as one of the most prevalent cancers worldwide. While the incidence of
gastric cancer in Western countries has notably diminished over the past century, it …

The host immune response plays a critical role in determining disease manifestations of
chronic infections. Inadequate immune response may fail to control infection, although in …

METHODS: A longitudinal cohort study was conducted on patients with consecutive CAG
adhering to endoscopic-histological surveillance. Patients were stratified for the …