Antibody-drug conjugates (ADCs) represent an important class of cancer therapies that have
revolutionized the treatment paradigm of solid tumors. To date, many ongoing studies of …

Fucoidan is an edible algae that has long been used as part of east Asians' diet. Recently,
various pharmacological activities of the polymer have been discovered including its ability …

Disseminated tumors are poorly accessible to nanoscale drug delivery systems because of
the vascular barrier, which attenuates extravasation at the tumor site. We investigated P …

CD8 T-cells are a critical brake on the initial development of tumors. In established tumors,
the presence of CD8 T-cells is correlated with a positive patient prognosis, although …

The relationship between cancer and thrombosis has been established since 1865 when
Armand Trousseau described superficial thrombophlebitis as forewarning sign of occult …

Platelets play a crucial role in the pathophysiological processes of hemostasis and
thrombosis. Increasing evidence indicates that they fulfill much broader roles in balancing …

Antibodies and related proteins comprise one of the largest and fastest-growing classes of
protein pharmaceuticals. A majority of such molecules are monoclonal antibodies; however …

Nanomaterial mediated cancer/tumor photo driven hyperthermia has obtained great
awareness. Nevertheless, it is a challenge for improving the hyperthermic efficacy lacking …

Unlike other blood cells, platelets are small anucleate structures derived from marrow
megakaryocytes. Thought for almost a century to possess solely hemostatic potentials …

Fucoidans are natural sulfated polysaccharides that have a wide range of biological
functions and are regarded as promising antitumor agents. The activity of various fucoidans …