[HTML][HTML] Non-vesicular release of alarmin prothymosin α complex associated with annexin-2 flop-out
H Ueda - Cells, 2023 - mdpi.com
Nuclear protein prothymosin α (ProTα) is a unique member of damage-associated molecular
patterns (DAMPs)/alarmins. ProTα prevents neuronal necrosis by causing a cell death mode …
patterns (DAMPs)/alarmins. ProTα prevents neuronal necrosis by causing a cell death mode …
Calcium mediated static and dynamic allostery in S100A12: Implications for target recognition by S100 proteins
Q Wang, C DiForte, A Aleshintsev, G Elci… - Protein …, 2024 - Wiley Online Library
Abstract Structure and functions of S100 proteins are regulated by two distinct calcium
binding EF hand motifs. In this work, we used solution‐state NMR spectroscopy to …
binding EF hand motifs. In this work, we used solution‐state NMR spectroscopy to …
Deciphering S100B Allosteric Signaling: The Role of a Peptide Target, TRTK-12, as an Ensemble Modulator
R Samanta, X Zhuang, KM Varney… - Journal of Chemical …, 2024 - ACS Publications
Allostery is an essential biological phenomenon in which perturbation at one site in a
biomolecule elicits a functional response at a distal location (s). It is integral to biological …
biomolecule elicits a functional response at a distal location (s). It is integral to biological …
Unveiling Conserved Allosteric Hot Spots in Protein Domains from Sequences
A Hacisuleyman, D Fasshauer - bioRxiv, 2024 - biorxiv.org
The amino acid sequence determines the structure, function, and dynamics of a protein. In
recent years, enormous progress has been made in translating sequence information into …
recent years, enormous progress has been made in translating sequence information into …