Age is the key risk factor for diseases and disabilities of the elderly. Efforts to tackle age-
related diseases and increase healthspan have suggested targeting the ageing process …

Aging is characterized by a progressive deterioration of physiological integrity, leading to
impaired functional ability and ultimately increased susceptibility to death. It is a major risk …

Background: Measures to quantify changes in the pace of biological aging in response to
intervention are needed to evaluate geroprotective interventions for humans. Previously, we …

With the rapid expansion of aging biology research, the identification and evaluation of
longevity interventions in humans have become key goals of this field. Biomarkers of aging …

Background Translating aging rejuvenation strategies into clinical practice has the potential
to address the unmet needs of the global aging population. However, to successfully do so …

As the global population becomes older, understanding the impact of aging on health and
disease becomes paramount. Recent advancements in multiomic technology have allowed …

THE PAST THREE DECADES OF RESEARCH ON SOCIAL determinants of health have
produced a wealth of evidence demonstrating how the conditions of daily life shape …

Abstract Purpose of Review Acceleration of biological processes of aging is hypothesized to
drive excess morbidity and mortality in socially disadvantaged populations. DNA methylation …

Biological aging is a proposed mechanism through which social determinants drive health
disparities. We conducted proof-of-concept testing of 8 DNA-methylation (DNAm) and blood …

Aging biomarkers are a combination of biological parameters to (i) assess age-related
changes,(ii) track the physiological aging process, and (iii) predict the transition into a …