Rational design of biomaterials to potentiate cancer thermal therapy

Y Zhu, Q Li, C Wang, Y Hao, N Yang, M Chen… - Chemical …, 2023 - ACS Publications
Cancer thermal therapy, also known as hyperthermia therapy, has long been exploited to
eradicate mass lesions that are now defined as cancer. With the development of …

Nanomaterials in anticancer applications and their mechanism of action-A review

CGA Das, VG Kumar, TS Dhas, V Karthick… - … , Biology and Medicine, 2023 - Elsevier
The current challenges in cancer treatment using conventional therapies have made the
emergence of nanotechnology with more advancements. The exponential growth of …

Multimodal imaging‐guided photothermal immunotherapy based on a versatile NIR‐II aggregation‐induced emission luminogen

D Yan, M Wang, Q Wu, N Niu, M Li… - Angewandte Chemie …, 2022 - Wiley Online Library
Synergistic photothermal immunotherapy has captured great attention owing to the mutually
strengthening therapeutic outcomes towards both original tumors and abscopal tumors …

Ce-net: Context encoder network for 2d medical image segmentation

Z Gu, J Cheng, H Fu, K Zhou, H Hao… - IEEE transactions on …, 2019 - ieeexplore.ieee.org
Medical image segmentation is an important step in medical image analysis. With the rapid
development of a convolutional neural network in image processing, deep learning has …

Bacteria-derived nanovesicles enhance tumour vaccination by trained immunity

G Liu, N Ma, K Cheng, Q Feng, X Ma, Y Yue… - Nature …, 2024 - nature.com
Trained immunity enhances the responsiveness of immune cells to subsequent infections or
vaccinations. Here we demonstrate that pre-vaccination with bacteria-derived outer …

Cancer immunotherapy based on image-guided STING activation by nucleotide nanocomplex-decorated ultrasound microbubbles

X Li, S Khorsandi, Y Wang, J Santelli, K Huntoon… - Nature …, 2022 - nature.com
The cytosolic innate immune sensor cyclic GMP-AMP synthase-stimulator of interferon
genes (cGAS-STING) pathway is crucial for priming adaptive antitumour immunity through …

Harnessing immune response using reactive oxygen Species-Generating/Eliminating inorganic biomaterials for disease treatment

C Zhao, H Deng, X Chen - Advanced Drug Delivery Reviews, 2022 - Elsevier
With the increasing understanding of various biological functions mediated by reactive
oxygen species (ROS) in the immune system, a number of studies have been designed to …

Polymeric nanoparticle-based nanovaccines for cancer immunotherapy

Y Zhang, J Chen, L Shi, F Ma - Materials Horizons, 2023 - pubs.rsc.org
Therapeutic cancer vaccines, which are designed to amplify tumor-specific T cell responses,
have been envisioned as one of the most powerful tools for effective cancer immunotherapy …

Intracellular Self‐Assembly Driven Nucleus‐Targeted Photo‐Immune Stimulator with Chromatin Decompaction Function for Robust Innate and Adaptive Antitumor …

X Zhao, K Zhang, Y Wang, W Jiang… - Advanced Functional …, 2022 - Wiley Online Library
Efficient nuclear DNA damage and release is highly recommended to improve the
photodynamic immunotherapy by eliciting innate immune response yet remains challenging …

Photoallosteric polymersomes toward on‐demand drug delivery and multimodal cancer immunotherapy

Y Zheng, Y Liu, Z Wu, C Peng, Z Wang… - Advanced …, 2023 - Wiley Online Library
Allosteric transitions can modulate the self‐assembly and biological function of proteins. It
remains, however, tremendously challenging to design synthetic allosteric polymeric …