Plant-derived antioxidants protect the nervous system from aging by inhibiting oxidative stress

X Cui, Q Lin, Y Liang - Frontiers in aging neuroscience, 2020 - frontiersin.org
Alzheimer's disease (AD) has become a major disease contributing to human death and is
thought to be closely related to the aging process. The rich antioxidant substances in plants …

Astaxanthin as a novel mitochondrial regulator: a new aspect of carotenoids, beyond antioxidants

Y Nishida, A Nawaz, K Hecht, K Tobe - Nutrients, 2021 - mdpi.com
Astaxanthin is a member of the carotenoid family that is found abundantly in marine
organisms, and has been gaining attention in recent years due to its varied biological …

Structures of astaxanthin and their consequences for therapeutic application

THP Brotosudarmo, L Limantara… - … Journal of Food …, 2020 - Wiley Online Library
Reactive oxygen species (ROS) are continuously generated as a by‐product of normal
aerobic metabolism. Elevated ROS formation leads to potential damage of biological …

Mechanisms of neuroplasticity and brain degeneration: strategies for protection during the aging process

M Toricelli, AAR Pereira, GS Abrao… - Neural regeneration …, 2021 - journals.lww.com
Aging is a dynamic and progressive process that begins at conception and continues until
death. This process leads to a decrease in homeostasis and morphological, biochemical …

[HTML][HTML] Acetaldehyde induces phosphorylation of dynamin-related protein 1 and mitochondrial dysfunction via elevating intracellular ROS and Ca2+ levels

T Yan, Y Zhao - Redox biology, 2020 - Elsevier
Excessive alcohol consumption impairs brain function and has been associated with an
earlier onset of neurodegenerative diseases such as Alzheimer's disease (AD) and …

Astaxanthin attenuates neuroinflammation contributed to the neuropathic pain and motor dysfunction following compression spinal cord injury

S Fakhri, L Dargahi, F Abbaszadeh, M Jorjani - Brain research bulletin, 2018 - Elsevier
Spinal cord injury (SCI) is a debilitating condition in which inflammatory responses in the
secondary phase of injury leads to long lasting sensory-motor dysfunction. The medicinal …

β‐Carotene attenuates lipopolysaccharide‐induced inflammation via inhibition of the NF‐κB, JAK2/STAT3 and JNK/p38 MAPK signaling pathways in macrophages

R Li, P Hong, X Zheng - Animal Science Journal, 2019 - Wiley Online Library
Abstract β‐carotene is one of the most abundant carotenoids, has potential anti‐
inflammatory effect, it has been reported that β‐carotene could suppress LPS‐induced …

OPFRs and BFRs induced A549 cell apoptosis by caspase-dependent mitochondrial pathway

X Yu, H Yin, H Peng, G Lu, Z Liu, Z Dang - Chemosphere, 2019 - Elsevier
Organophosphate flame retardants (OPFRs) and brominated flame retardants (BFRs) are
frequently detected in indoor environment at high levels, posing health risks to humans …

Plant polyphenols: potential antidotes for lead exposure

Y Li, H Lv, C Xue, N Dong, C Bi, A Shan - Biological trace element …, 2021 - Springer
Lead is one of the most common heavy metal elements and has high biological toxicity.
Long-term lead exposure will induce the contamination of animal feed, water, and food …

Glial cell AMPA receptors in nervous system health, injury and disease

M Ceprian, D Fulton - International journal of molecular sciences, 2019 - mdpi.com
Glia form a central component of the nervous system whose varied activities sustain an
environment that is optimised for healthy development and neuronal function. Alpha-amino …