Advances in single-cell transcriptomics in animal research
Y Yan, S Zhu, M Jia, X Chen, W Qi, F Gu… - Journal of Animal …, 2024 - Springer
Understanding biological mechanisms is fundamental for improving animal production and
health to meet the growing demand for high-quality protein. As an emerging biotechnology …
health to meet the growing demand for high-quality protein. As an emerging biotechnology …
[HTML][HTML] Single-cell RNA sequencing and UPHLC-MS/MS targeted metabolomics offer new insights into the etiological basis for male cattle-yak sterility
X Wang, J Pei, L Xiong, Y Kang, S Guo, M Cao… - International Journal of …, 2023 - Elsevier
The variety of species can be efficiently increased by interspecific hybridization. However,
because the males in the hybrid progeny are usually sterile, this heterosis cannot be …
because the males in the hybrid progeny are usually sterile, this heterosis cannot be …
[HTML][HTML] Integrative analysis of single-nucleus RNA-seq and bulk RNA-seq reveals germline cells development dynamics and niches in the Pacific oyster gonad
H Wang, H Yu, Q Li - Iscience, 2024 - cell.com
Gametogenesis drives the maturation of germ cell precursors into functional gametes,
facilitated by interactions with the niche environment. However, the molecular mechanisms …
facilitated by interactions with the niche environment. However, the molecular mechanisms …
Single-Cell Transcriptome Sequencing Reveals Molecular Expression Differences and Marker Genes in Testes during the Sexual Maturation of Mongolian Horses
Y Liu, M Du, X Li, L Zhang, B Zhao, N Wang… - Animals, 2024 - mdpi.com
Simple Summary The results of this research revealed significant differences in the tissue
morphology and gene expression profiles of Mongolian horses based on age. Specifically …
morphology and gene expression profiles of Mongolian horses based on age. Specifically …
Integrated single cell transcriptome sequencing analysis reveals species‐specific genes and molecular pathways for pig spermiogenesis
YD Zhao, CX Yang, ZQ Du - Reproduction in Domestic Animals, 2023 - Wiley Online Library
Mammalian spermatogenesis is a highly complicated and intricately organized process
involving spermatogonia propagation (mitosis) and meiotic differentiation into mature sperm …
involving spermatogonia propagation (mitosis) and meiotic differentiation into mature sperm …
Adult human, but not rodent, spermatogonial stem cells retain states with a foetal-like signature
Spermatogenesis involves a complex process of cellular differentiation maintained by
spermatogonial stem cells (SSCs). Being critical to male reproduction, it is generally …
spermatogonial stem cells (SSCs). Being critical to male reproduction, it is generally …
Mechanisms of imbalanced testicular homeostasis in infancy due to aberrant histone acetylation in undifferentiated spermatogonia under different concentrations of Di …
Y Tian, J Guo, L Hua, Y Jiang, W Ge, X Zhang… - Environmental …, 2024 - Elsevier
Abstract Di (2-ethylhexyl) phthalate (DEHP), identified as an endocrine-disrupting chemical,
is associated with reproductive toxicity. This association is particularly noteworthy in …
is associated with reproductive toxicity. This association is particularly noteworthy in …
Single-Cell Transcriptomic Analysis Revealed the Cell Population Changes and Cell–Cell Communication in the Liver of a Carnivorous Fish in Response to High …
S Xie, J Xu, L Chen, Y Qi, H Yang, B Tan - The Journal of Nutrition, 2024 - Elsevier
Background Carnivorous fish have a low carbohydrate utilization ability, and the physiologic
and molecular basis of glucose intolerance has not been fully illustrated. Objectives This …
and molecular basis of glucose intolerance has not been fully illustrated. Objectives This …
Revelation of genetic diversity and genomic footprints of adaptation in Indian pig breeds
In the present study, the genetic diversity measures among four Indian domestic breeds of
pig namely Agonda Goan, Ghurrah, Ghungroo, and Nicobari, of different agro-climatic …
pig namely Agonda Goan, Ghurrah, Ghungroo, and Nicobari, of different agro-climatic …
[HTML][HTML] Germ cells do not progress through spermatogenesis in the infertile zebrafish testis
AL Sposato, DR Llewellyn, JM Weber, HL Hollins… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Vertebrate spermatogonial stem cells maintain sperm production over the lifetime of an
animal but fertility declines with age. While morphological studies have greatly informed our …
animal but fertility declines with age. While morphological studies have greatly informed our …