Molecular mechanism of Aspergillus fumigatus adherence to host constituents

DC Sheppard - Current opinion in microbiology, 2011 - Elsevier
Inhaled conidia of Aspergillus fumigatus rapidly adhere to pulmonary epithelial cells and
other host constituents. Identifying molecular mechanisms underlying A. fumigatus …

A study of the Candida albicans cell wall proteome

L Castillo, E Calvo, AI Martínez, J Ruiz‐Herrera… - …, 2008 - Wiley Online Library
Considering the importance of proteins in the structure and function of the cell wall of
Candida albicans, we analyzed the cell wall subproteome of this important human pathogen …

[HTML][HTML] N-cadherin mediates endocytosis of Candida albicans by endothelial cells

QT Phan, RA Fratti, NV Prasadarao, JE Edwards… - Journal of Biological …, 2005 - ASBMB
Candida albicans is the most common cause of fungal bloodstream infections. To invade the
deep tissues, blood-borne organisms must cross the endothelial cell lining of the …

Candida albicans Als proteins mediate aggregation with bacteria and yeasts

SA Klotz, NK Gaur, R De Armond, D Sheppard… - Medical …, 2007 - academic.oup.com
Candida albicans occupies a microniche on mucosal surfaces where diverse microbial
populations interact within a biofilm. Because C. albicans is intimately involved with other …

[HTML][HTML] Proteinous components of neutrophil extracellular traps are arrested by the cell wall proteins of Candida albicans during fungal infection, and can be used in …

J Karkowska-Kuleta, M Smolarz, K Seweryn-Ozog… - Cells, 2021 - mdpi.com
One of defense mechanisms of the human immune system to counteract infection by the
opportunistic fungal pathogen Candida albicans is the recruitment of neutrophils to the site …

[HTML][HTML] Moonlighting proteins in medically relevant fungi

VJ Arvizu-Rubio, LC García-Carnero, HM Mora-Montes - PeerJ, 2022 - peerj.com
Moonlighting proteins represent an intriguing area of cell biology, due to their ability to
perform two or more unrelated functions in one or many cellular compartments. These …

Candida albicans CUG mistranslation is a mechanism to create cell surface variation

I Miranda, A Silva-Dias, R Rocha, R Teixeira-Santos… - MBio, 2013 - Am Soc Microbiol
In the human fungal pathogen Candida albicans, the CUG codon is translated 97% of the
time as serine and 3% of the time as leucine, which potentially originates an array of …

[HTML][HTML] Promising immunotherapeutic targets for treating candidiasis

Z Feng, H Lu, Y Jiang - Frontiers in Cellular and Infection …, 2024 - frontiersin.org
In the last twenty years, there has been a significant increase in invasive fungal infections,
which has corresponded with the expanding population of individuals with compromised …

Proteolytic cleavage of covalently linked cell wall proteins by Candida albicans Sap9 and Sap10

L Schild, A Heyken, PWJ de Groot, E Hiller… - Eukaryotic …, 2011 - Am Soc Microbiol
The cell wall of the human-pathogenic fungus Candida albicans is a robust but also dynamic
structure which mediates adaptation to changing environmental conditions during infection …

Threonine-Rich Repeats Increase Fibronectin Binding in the Candida albicans Adhesin Als5p

JM Rauceo, R De Armond, H Otoo, PC Kahn… - Eukaryotic …, 2006 - Am Soc Microbiol
Commensal and pathogenic states of Candida albicans depend on cell surface-expressed
adhesins, including those of the Als family. Mature Als proteins consist of a 300-residue N …