FOXO transcription factor family in cancer and metastasis

Y Jiramongkol, EWF Lam - Cancer and Metastasis Reviews, 2020 - Springer
Forkhead box O (FOXO) transcription factors regulate diverse biological processes, affecting
development, metabolism, stem cell maintenance and longevity. They have also been …

microRNAs: new prognostic, diagnostic, and therapeutic biomarkers in cervical cancer

JS Nahand, S Taghizadeh‐boroujeni… - Journal of cellular …, 2019 - Wiley Online Library
Cervical cancer is as a kind of cancer beginning from the cervix. Given that cervical cancer
could be observed in women who infected with papillomavirus, regular oral contraceptives …

Role of Forkhead Box Class O proteins in cancer progression and metastasis

CG Kim, H Lee, N Gupta, S Ramachandran… - Seminars in cancer …, 2018 - Elsevier
It is now widely accepted that several gene alterations including transcription factors are
critically involved in cancer progression and metastasis. Forkhead Box Class O proteins …

Current perspective on the regulation of FOXO4 and its role in disease progression

W Liu, Y Li, B Luo - Cellular and Molecular Life Sciences, 2020 - Springer
Abstract Forkhead box O4 (FOXO4) is a member of the FOXO family that regulates a number
of genes involved in metabolism, cell cycle, apoptosis, and cellular homeostasis via …

MicroRNAs in gynecological cancers: Small molecules with big implications

SK Srivastava, A Ahmad, H Zubair, O Miree, S Singh… - Cancer letters, 2017 - Elsevier
Gynecological cancers (GCs) are often diagnosed at advanced stages, limiting the efficacy
of available therapeutic options. Thus, there remains an urgent and unmet need for …

MiR-150 promotes cellular metastasis in non-small cell lung cancer by targeting FOXO4

H Li, R Ouyang, Z Wang, W Zhou, H Chen, Y Jiang… - Scientific reports, 2016 - nature.com
Previous studies have shown that dysregulation of microRNA-150 (miR-150) is associated
with aberrant proliferation of human non-small cell lung cancer (NSCLC) cells. However …

Role of FoxO proteins in cellular response to antitumor agents

GL Beretta, C Corno, N Zaffaroni, P Perego - Cancers, 2019 - mdpi.com
FoxO proteins (FoxOs) are transcription factors with a common DNA binding domain that
confers selectivity for DNA interaction. In human cells, four proteins (FoxO1, FoxO3, FoxO4 …

[HTML][HTML] MicroRNA-150 promotes cell proliferation, migration, and invasion of cervical cancer through targeting PDCD4

Z Zhang, J Wang, J Li, X Wang, W Song - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Recent studies have showed that microRNA-150 (miR-150) is up-regulated in various
cancers including cervical cancer. However, the specific mechanism of miR-150 in the …

MicoRNA-425-5p is a potential prognostic biomarker for cervical cancer

L Sun, R Jiang, J Li, B Wang, C Ma… - Annals of clinical …, 2017 - journals.sagepub.com
Background MicroRNAs have been implicated in many biological pathways involved in
tumourigenesis and can serve as prognostic biomarkers in many cancer types. The present …

[HTML][HTML] Long noncoding RNA FOXD3-AS1 regulates oxidative stress-induced apoptosis via sponging microRNA-150

D Zhang, H Lee, JA Haspel, Y Jin - The FASEB Journal, 2017 - ncbi.nlm.nih.gov
The function of most human long noncoding RNAs (lncRNAs) remains unclear. Our studies
identified a highly up-regulated mammalian lncRNA, FOXD3-AS1, known as linc1623 in …