Dosage sensitivity and exon shuffling shape the landscape of polymorphic duplicates in Drosophila and humans
Despite polymorphic duplicate genes' importance for the early stages of duplicate gene
evolution, they are less studied than old gene duplicates. Two essential questions thus …
evolution, they are less studied than old gene duplicates. Two essential questions thus …
Polygenic signals of sex differences in selection in humans from the UK Biobank
Sex differences in the fitness effects of genetic variants can influence the rate of adaptation
and the maintenance of genetic variation. For example,“sexually antagonistic”(SA) variants …
and the maintenance of genetic variation. For example,“sexually antagonistic”(SA) variants …
A putative de novo evolved gene required for spermatid chromatin condensation in Drosophila melanogaster
EL Rivard, AG Ludwig, PH Patel, A Grandchamp… - PLoS …, 2021 - journals.plos.org
Comparative genomics has enabled the identification of genes that potentially evolved de
novo from non-coding sequences. Many such genes are expressed in male reproductive …
novo from non-coding sequences. Many such genes are expressed in male reproductive …
Neofunctionalization of tandem duplicate genes encoding putative β-L-arabinofuranosidases in Arabidopsis
Tandem duplication, one of the major types of duplication, provides the raw material for the
evolution of divergent functions. In this study, we identified 1 pair of tandem duplicate genes …
evolution of divergent functions. In this study, we identified 1 pair of tandem duplicate genes …
HP6/Umbrea is dispensable for viability and fertility, suggesting essentiality of newly evolved genes is rare
S Grill, A Riley, M Selvaraj… - Proceedings of the …, 2023 - National Acad Sciences
The newly evolved gene Heterochromatin Protein 6 (HP6), which has been previously
classified as essential, challenged the dogma that functions required for viability are only …
classified as essential, challenged the dogma that functions required for viability are only …
Genomic analyses of new genes and their phenotypic effects reveal rapid evolution of essential functions in Drosophila development
It is a conventionally held dogma that the genetic basis underlying development is
conserved in a long evolutionary time scale. Ample experiments based on mutational …
conserved in a long evolutionary time scale. Ample experiments based on mutational …
Sex-linked gene traffic underlies the acquisition of sexually dimorphic UV color vision in Heliconius butterflies
M Chakraborty, AG Lara, A Dang… - Proceedings of the …, 2023 - National Acad Sciences
The acquisition of novel sexually dimorphic traits poses an evolutionary puzzle: How do new
traits arise and become sex-limited? Recently acquired color vision, sexually dimorphic in …
traits arise and become sex-limited? Recently acquired color vision, sexually dimorphic in …
Mitochondrially mediated RNA interference, a retrograde signaling system affecting nuclear gene expression
Several functional classes of short noncoding RNAs are involved in manifold regulatory
processes in eukaryotes, including, among the best characterized, miRNAs. One of the most …
processes in eukaryotes, including, among the best characterized, miRNAs. One of the most …
DNA transposons mediate duplications via transposition-independent and-dependent mechanisms in metazoans
Despite long being considered as “junk”, transposable elements (TEs) are now accepted as
catalysts of evolution. One example is Mutator-like elements (MULEs, one type of terminal …
catalysts of evolution. One example is Mutator-like elements (MULEs, one type of terminal …
Convergent evolution in a murine intestinal parasite rapidly created the TGM family of molecular mimics to suppress the host immune response
RM Maizels, SJ Newfeld - Genome biology and evolution, 2023 - academic.oup.com
Abstract The Transforming Growth Factor-β mimic (TGM) multigene family was recently
discovered in the murine intestinal parasite Heligmosomoides polygyrus. This family was …
discovered in the murine intestinal parasite Heligmosomoides polygyrus. This family was …