Dosage sensitivity and exon shuffling shape the landscape of polymorphic duplicates in Drosophila and humans

D Zhang, L Leng, C Chen, J Huang, Y Zhang… - Nature Ecology & …, 2022 - nature.com
Despite polymorphic duplicate genes' importance for the early stages of duplicate gene
evolution, they are less studied than old gene duplicates. Two essential questions thus …

Polygenic signals of sex differences in selection in humans from the UK Biobank

F Ruzicka, L Holman, T Connallon - PLoS Biology, 2022 - journals.plos.org
Sex differences in the fitness effects of genetic variants can influence the rate of adaptation
and the maintenance of genetic variation. For example,“sexually antagonistic”(SA) variants …

A putative de novo evolved gene required for spermatid chromatin condensation in Drosophila melanogaster

EL Rivard, AG Ludwig, PH Patel, A Grandchamp… - PLoS …, 2021 - journals.plos.org
Comparative genomics has enabled the identification of genes that potentially evolved de
novo from non-coding sequences. Many such genes are expressed in male reproductive …

Neofunctionalization of tandem duplicate genes encoding putative β-L-arabinofuranosidases in Arabidopsis

F Tao, V Sollapura, LS Robert, C Fan - Plant Physiology, 2023 - academic.oup.com
Tandem duplication, one of the major types of duplication, provides the raw material for the
evolution of divergent functions. In this study, we identified 1 pair of tandem duplicate genes …

HP6/Umbrea is dispensable for viability and fertility, suggesting essentiality of newly evolved genes is rare

S Grill, A Riley, M Selvaraj… - Proceedings of the …, 2023 - National Acad Sciences
The newly evolved gene Heterochromatin Protein 6 (HP6), which has been previously
classified as essential, challenged the dogma that functions required for viability are only …

Genomic analyses of new genes and their phenotypic effects reveal rapid evolution of essential functions in Drosophila development

S Xia, NW VanKuren, C Chen, L Zhang… - PLoS …, 2021 - journals.plos.org
It is a conventionally held dogma that the genetic basis underlying development is
conserved in a long evolutionary time scale. Ample experiments based on mutational …

Sex-linked gene traffic underlies the acquisition of sexually dimorphic UV color vision in Heliconius butterflies

M Chakraborty, AG Lara, A Dang… - Proceedings of the …, 2023 - National Acad Sciences
The acquisition of novel sexually dimorphic traits poses an evolutionary puzzle: How do new
traits arise and become sex-limited? Recently acquired color vision, sexually dimorphic in …

Mitochondrially mediated RNA interference, a retrograde signaling system affecting nuclear gene expression

F Plazzi, Y Le Cras, A Formaggioni, M Passamonti - Heredity, 2024 - nature.com
Several functional classes of short noncoding RNAs are involved in manifold regulatory
processes in eukaryotes, including, among the best characterized, miRNAs. One of the most …

DNA transposons mediate duplications via transposition-independent and-dependent mechanisms in metazoans

S Tan, H Ma, J Wang, M Wang, M Wang, H Yin… - Nature …, 2021 - nature.com
Despite long being considered as “junk”, transposable elements (TEs) are now accepted as
catalysts of evolution. One example is Mutator-like elements (MULEs, one type of terminal …

Convergent evolution in a murine intestinal parasite rapidly created the TGM family of molecular mimics to suppress the host immune response

RM Maizels, SJ Newfeld - Genome biology and evolution, 2023 - academic.oup.com
Abstract The Transforming Growth Factor-β mimic (TGM) multigene family was recently
discovered in the murine intestinal parasite Heligmosomoides polygyrus. This family was …