[HTML][HTML] Taurine and its analogs in neurological disorders: Focus on therapeutic potential and molecular mechanisms

M Jakaria, S Azam, ME Haque, SH Jo, MS Uddin… - Redox biology, 2019 - Elsevier
Taurine is a sulfur-containing amino acid and known as semi-essential in mammals and is
produced chiefly by the liver and kidney. It presents in different organs, including retina …

Neuroinflammation: a potential risk for dementia

MA Ahmad, O Kareem, M Khushtar, M Akbar… - International journal of …, 2022 - mdpi.com
Dementia is a neurodegenerative condition that is considered a major factor contributing to
cognitive decline that reduces independent function. Pathophysiological pathways are not …

Circadian and sleep dysfunction in Alzheimer's disease

MS Uddin, D Tewari, A Al Mamun, MT Kabir… - Ageing Research …, 2020 - Elsevier
Alzheimer's disease (AD) is a devastating and irreversible cognitive impairment and the
most common type of dementia. Along with progressive cognitive impairment, dysfunction of …

Emerging promise of sulforaphane-mediated Nrf2 signaling cascade against neurological disorders

MS Uddin, A Al Mamun, M Jakaria… - Science of the Total …, 2020 - Elsevier
Neurological disorders represent a great challenge and are the leading cause of death and
disability globally. Although numerous complicated mechanisms are involved in the …

Hesperetin confers neuroprotection by regulating Nrf2/TLR4/NF-κB signaling in an Aβ mouse model

M Ikram, T Muhammad, SU Rehman, A Khan… - Molecular …, 2019 - Springer
Hesperetin is a bioactive flavonoid in the body, produced from hesperidin. No
comprehensive studies have shown its protective effects in neurodegenerative disorders …

Neuroprotective role of polyphenols against oxidative stress-mediated neurodegeneration

MS Uddin, A Al Mamun, MT Kabir, J Ahmad… - European journal of …, 2020 - Elsevier
Neurodegenerative diseases (NDs) are characterized by disorders with progressive
deterioration of the structure and/or function of neurons. Genetic mutations can lead to many …

Role of phenolic compounds in human disease: current knowledge and future prospects

MM Rahman, MS Rahaman, MR Islam, F Rahman… - Molecules, 2021 - mdpi.com
Inflammation is a natural protective mechanism that occurs when the body's tissue
homeostatic mechanisms are disrupted by biotic, physical, or chemical agents. The immune …

Emerging therapeutic potentials of dual‐acting MAO and AChE inhibitors in Alzheimer's and Parkinson's diseases

B Mathew, DGT Parambi, GE Mathew… - Archiv der …, 2019 - Wiley Online Library
No drug has been approved to prevent neuronal cell loss in patients suffering from
Parkinson's disease (PD) or Alzheimer's disease (AD); despite increased comprehension of …

Melatonin in Alzheimer's disease: a latent endogenous regulator of neurogenesis to mitigate Alzheimer's neuropathology

MF Hossain, MS Uddin, GMS Uddin… - Molecular …, 2019 - Springer
Melatonin, a pineal gland synthesized neurohormone is known as a multifunctioning
pleiotropic agent which has a wide range of neuroprotective role in manifold age-related …

Cholinesterase inhibitors for Alzheimer's disease: multitargeting strategy based on anti-Alzheimer's drugs repositioning

MT Kabir, MS Uddin, M Begum… - Current …, 2019 - ingentaconnect.com
In the brain, acetylcholine (ACh) is regarded as one of the major neurotransmitters. During
the advancement of Alzheimer's disease (AD) cholinergic deficits occur and this can lead to …