Precise nanomedicine for intelligent therapy of cancer

H Chen, Z Gu, H An, C Chen, J Chen, R Cui… - Science China …, 2018 - Springer
Precise nanomedicine has been extensively explored for efficient cancer imaging and
targeted cancer therapy, as evidenced by a few breakthroughs in their preclinical and …

Review of methods for intraoperative margin detection for breast conserving surgery

BW Maloney, DM McClatchy, BW Pogue… - … of biomedical optics, 2018 - spiedigitallibrary.org
Breast conserving surgery (BCS) is an effective treatment for early-stage cancers as long as
the margins of the resected tissue are free of disease according to consensus guidelines for …

Prospective testing of clinical Cerenkov luminescence imaging against standard-of-care nuclear imaging for tumour location

EC Pratt, M Skubal, B Mc Larney… - Nature biomedical …, 2022 - nature.com
In oncology, the feasibility of Cerenkov luminescence imaging (CLI) has been assessed by
imaging superficial lymph nodes in a few patients undergoing diagnostic 18F-fluoro-2 …

PET/fluorescence imaging: An overview of the chemical strategies to build dual imaging tools

J Ariztia, K Solmont, NP Moïse, S Specklin… - Bioconjugate …, 2022 - ACS Publications
Molecular imaging is a biomedical research discipline that has quickly emerged to afford the
observation, characterization, monitoring, and quantification of biomarkers and biological …

[HTML][HTML] Cerenkov luminescence imaging: physics principles and potential applications in biomedical sciences

E Ciarrocchi, N Belcari - EJNMMI physics, 2017 - Springer
Cerenkov luminescence imaging (CLI) is a novel imaging modality to study charged
particles with optical methods by detecting the Cerenkov luminescence produced in tissue …

Intraoperative assessment of tumor resection margins in breast-conserving surgery using 18F-FDG Cerenkov luminescence imaging: a first-in-human feasibility study

MR Grootendorst, M Cariati, SE Pinder… - Journal of Nuclear …, 2017 - Soc Nuclear Med
In early-stage breast cancer, the primary treatment option for most women is breast-
conserving surgery (BCS). There is a clear need for more accurate techniques to assess …

[HTML][HTML] Surgical advances in osteosarcoma

MJ Brookes, CD Chan, B Baljer, S Wimalagunaratna… - Cancers, 2021 - mdpi.com
Simple Summary Osteosarcoma (OS) is the most common bone cancer in children. OS most
commonly arises in the legs, but can arise in any bone, including the spine, head or neck …

Radioluminescence in biomedicine: physics, applications, and models

JS Klein, C Sun, G Pratx - Physics in Medicine & Biology, 2019 - iopscience.iop.org
The electromagnetic spectrum contains different frequency bands useful for medical imaging
and therapy. Short wavelengths (ionizing radiation) are commonly used for radiological and …

[HTML][HTML] Gold nanoparticles meet medical radionuclides

N Daems, C Michiels, S Lucas, S Baatout… - Nuclear Medicine and …, 2021 - Elsevier
Thanks to their unique optical and physicochemical properties, gold nanoparticles have
gained increased interest as radiosensitizing, photothermal therapy and optical imaging …

New intraoperative imaging technologies: Innovating the surgeon's eye toward surgical precision

P Mascagni, F Longo, M Barberio… - Journal of surgical …, 2018 - Wiley Online Library
Imaging is one of the pillars for the ongoing evolution of surgical oncology toward a
precision paradigm. In the present overview, some established or emerging intraoperative …