Three theories of regeneration dominate neuroscience today, all purporting to explain why
the adult central nervous system (CNS) cannot regenerate. One theory proposes that Nogo …

The progression of a tumour from one of benign and delimited growth to one that is invasive
and metastatic is the major cause of poor clinical outcome in cancer patients. The invasion …

Abstract Small GTPases of the Rho family are involved in the regulation of a variety of
cellular processes, such as the organization of the microfilamental network, cell‐cell contact …

In the present study, we addressed the question of a putative relevance of Rho proteins in
tumour progression by analysing their expression on protein and mRNA level in breast …

Kidney injury molecule-1 (KIM-1) is a receptor for the “eat me” signal, phosphatidylserine, on
apoptotic cells. The specific upregulation of KIM-1 by injured tubular epithelial cells (TECs) …

Several clinical trials have shown the beneficial effects of statins in the prevention of
coronary heart disease. Additionally, statins promote apoptosis in vascular smooth muscle …

Previous data indicated that Pseudomonas aeruginosa exoenzyme S (ExoS) ADP-
ribosylated Ras at multiple sites. One site appeared to be Arg 41, but the second site could …

The mouse F9 embryonal carcinoma cell line is ideally suited to study the epithelial-to-
mesenchymal transition accompanying the differentiation of primitive to parietal …

Abstract Gα12/13, which belongs to the Gα12 family, participates in the regulation of diverse
physiologic processes. In view of the control of Gα12/13 in cell proliferation, this study …

The effect of KCl on ADP-ribosylation of the recombinant RhoA protein catalyzed by the
Clostridium botulinum C3 enzyme was studied. When the recombinant glutathione S …