The dynamic physiological changes that occur in the maternal-placental-fetal unit during
pregnancy influence the pharmacokinetic processes of drug absorption, distribution and …

Breastfeeding has positive health consequences for both the breastfed infant and the
nursing mother. 1, 2 Although information on drug use during lactation is available through …

Background Thiopurines are widely used to maintain remission in inflammatory bowel
disease. Treatment during pregnancy is generally recommended to improve the chance of a …

OBJECTIVE: The authors reviewed the risks and benefits regarding the use of psychiatric
medications during breast-feeding as they relate to the health and well-being of mothers and …

Rapid changes in organ development and function occur during the neonatal period. During
this period the central nervous system is in a rapid growth rate and highly vulnerable to toxic …

The factors that affect M/P (milk-to-plasma) ratios of several compounds were assessed in
vitro using samples collected from four healthy lactating women. Three drugs were studied …

Objective: Benzodiazepines are common therapies for mental illness and insomnia, and are
used during pregnancy and lactation. Although benzodiazepines have been shown to be …

In its report Breastfeeding: WIC's Efforts to Promote Breastfeeding Have Increased (1993),
the US General Accounting Office (GAO) recommended that the US Department of …

Endocrine system is one of the most sensitive communication networks of the human body,
which influences all aspects of human health and well-being, including reproductive …

The excretion of loratadine, a new nonsedating antihistamine, into human breast milk was
studied in six lactating nonpregnant volunteers. Each volunteer received one 40‐mg …