Insights and implications of sexual dimorphism in osteoporosis

YY Zhang, N Xie, XD Sun, EC Nice, YC Liou, C Huang… - Bone research, 2024 - nature.com
Osteoporosis, a metabolic bone disease characterized by low bone mineral density and
deterioration of bone microarchitecture, has led to a high risk of fatal osteoporotic fractures …

Molecular basis of bone aging

A Corrado, D Cici, C Rotondo, N Maruotti… - International journal of …, 2020 - mdpi.com
A decline in bone mass leading to an increased fracture risk is a common feature of age-
related bone changes. The mechanisms underlying bone senescence are very complex and …

Osteoporosis and alveolar bone health in Periodontitis Niche: a predisposing factors-centered review

L Zhu, C Zhou, S Chen, D Huang, Y Jiang, Y Lan… - Cells, 2022 - mdpi.com
Periodontitis is a periodontal inflammatory condition that results from disrupted periodontal
host–microbe homeostasis, manifested by the destruction of tooth-supporting structures …

Sex differences in body composition, metabolism‐related hormones, and energy homeostasis during aging in Wistar rats

S Quirós Cognuck, WL Reis, M Silva… - Physiological …, 2020 - Wiley Online Library
Aging affects the body composition and balance of energy metabolism. Here, we collected in
a single work several physiological parameters to show how aging and sex differences can …

Effect of body mass index on bone mineral density is age-specific

L Cherukuri, A Kinninger, D Birudaraju… - Nutrition, Metabolism …, 2021 - Elsevier
Background and aims Obesity and osteoporosis are two important and growing public
health problems worldwide. Body mass index (BMI) has been found to be inversely related …

Associations of physical activity with sarcopenia and sarcopenic obesity in middle-aged and older adults: The Louisiana osteoporosis study

Y Du, T Xu, Z Yin, S Espinoza, Y Xie, C Gentry, Q Tian… - BMC Public Health, 2022 - Springer
Background This study examined the associations between physical activity, obesity, and
sarcopenia in middle-aged and older adults. Methods We analyzed the data of 8, 919 study …

Association of alternative dietary patterns with osteoporosis and fracture risk in older people: A scoping review

H Chen, C Avgerinou - Nutrients, 2023 - mdpi.com
Purpose: Although the Mediterranean diet has been associated with a lower risk of hip
fracture, the effect of other dietary patterns on bone density and risk of fracture is unknown …

Prevalence and consequences of malnutrition and malnourishment in older individuals admitted to hospital with a hip fracture

TS Han, K Yeong, R Lisk, D Fluck, CH Fry - European Journal of Clinical …, 2021 - nature.com
Background/objectives Major causes of hip fractures are osteoporosis and falls, both of
which are determined by nutrition. Information on the nutritional status of patients admitted to …

MicroRNAs regulating TGFβ and BMP signaling in the osteoblast lineage

J Garcia, AM Delany - Bone, 2021 - Elsevier
This review showcases miRNAs contributing to the regulation of bone forming osteoblasts
through their effects on the TGFβ and BMP pathways, with a focus on ligands, receptors and …

Estrogen and estrogen receptors mediate the mechanobiology of bone disease and repair

V Shi, EF Morgan - Bone, 2024 - Elsevier
It is well understood that the balance of bone formation and resorption is dependent on both
mechanical and biochemical factors. In addition to cell-secreted cytokines and growth …