Bacteriophages and phage-delivered CRISPR-Cas system as antibacterial therapy

TK Yeh, SS Jean, YL Lee, MC Lu, WC Ko, HJ Lin… - International journal of …, 2022 - Elsevier
Multidrug-resistant (MDR) bacterial infections in humans are increasing worldwide. The
global spread of antimicrobial resistance poses a considerable threat to human health …

Application of Microbiome Management in Therapy for Clostridioides difficile Infections: From Fecal Microbiota Transplantation to Probiotics to Microbiota-Preserving …

CW Chiu, PJ Tsai, CC Lee, WC Ko, YP Hung - Pathogens, 2021 - mdpi.com
Oral vancomycin and metronidazole, though they are the therapeutic choice for
Clostridioides difficile infections (CDIs), also markedly disturb microbiota, leading to a …

Clostridioides difficile infection: an emerging zoonosis?

CS Tsai, YP Hung, JC Lee, LS Syue… - Expert Review of Anti …, 2021 - Taylor & Francis
Introduction Clostridioides difficile (C. difficile) infection (CDI) is the most common cause of
antibiotic-associated diarrhea and one of the common infections in healthcare facilities. In …

The Role of Toll-Like Receptor-2 in Clostridioides difficile Infection: Evidence From a Mouse Model and Clinical Patients

YH Lai, BY Tsai, CY Hsu, YH Chen, PH Chou… - Frontiers in …, 2021 - frontiersin.org
Background Clostridioides difficile is the leading cause of nosocomial infectious diarrhea.
Toll-like receptors (TLRs) are the major components of innate immunity that sense …

[HTML][HTML] Cytomegalovirus proctitis in non-human immunodeficiency virus infected patients: a case report and literature review

KY Liu, HM Chao, YJ Lu, YS Su, WS Lee - Journal of Microbiology …, 2022 - Elsevier
Cytomegalovirus (CMV) infection is associated with significant morbidity and mortality in
both immunocompetent and immunocompromised patients. CMV is a ubiquitous …

[HTML][HTML] Inhibition of spores to prevent the recurrence of Clostridioides difficile infection-A possibility or an improbability?

CW Chiu, PJ Tsai, CC Lee, WC Ko, YP Hung - Journal of Microbiology …, 2021 - Elsevier
Clostridioides difficile is one of the most common nosocomial gastrointestinal pathogens,
and recurrence is a problematic issue because approximately 20–30% of patients …

Clinical significance of toxigenic Clostridioides difficile growth in stool cultures during the era of nonculture methods for the diagnosis of C. difficile infection

CC Lee, JC Lee, CW Chiu, PJ Tsai, WC Ko… - Microbiology …, 2021 - Am Soc Microbiol
The importance of the detection of relevant toxins or toxin genes to diagnose Clostridioides
difficile infection (CDI) or the prediction of clinical outcomes of CDI has been emphasized in …

Clustering Disease of Clostridioides Difficile Infection: Implication for the Management in Internal Medicine

P Crispino - Microbiology Research, 2023 - mdpi.com
Clostridioides difficile is a bacterium responsible for a healthcare-associated gastrointestinal
infection, primarily affecting people who have undergone prolonged antibiotic treatment or …

Rapid detection of gastrointestinal pathogens using a multiplex polymerase chain reaction gastrointestinal panel and its role in antimicrobial stewardship

CH Chen, YY Low, YH Liu, HH Lin, MW Ho… - Journal of Microbiology …, 2023 - Elsevier
Abstract Objectives The FilmArray gastrointestinal panel (FAGIP) is widely used to detect
infectious diarrhoea due to its outstanding sensitivity compared to conventional methods, but …

[HTML][HTML] The emergence of Clostridioides difficile PCR ribotype 127 at a hospital in northeastern Taiwan

BY Tsai, CC Chien, SH Huang, JY Zheng… - Journal of Microbiology …, 2022 - Elsevier
Background Several studies have highlighted the incidence of Clostridioides difficile
infections (CDIs) in Taiwan and certain ribotypes have been related to severe clinical …