Inflammation and atherosclerosis: signaling pathways and therapeutic intervention
P Kong, ZY Cui, XF Huang, DD Zhang… - Signal transduction and …, 2022 - nature.com
Atherosclerosis is a chronic inflammatory vascular disease driven by traditional and
nontraditional risk factors. Genome-wide association combined with clonal lineage tracing …
nontraditional risk factors. Genome-wide association combined with clonal lineage tracing …
[HTML][HTML] The ketogenic diet and cardiovascular diseases
D Dyńka, K Kowalcze, A Charuta, A Paziewska - Nutrients, 2023 - mdpi.com
The most common and increasing causes of death worldwide are cardiovascular diseases
(CVD). Taking into account the fact that diet is a key factor, it is worth exploring this aspect of …
(CVD). Taking into account the fact that diet is a key factor, it is worth exploring this aspect of …
The selective NLRP3 inhibitor MCC950 hinders atherosclerosis development by attenuating inflammation and pyroptosis in macrophages
W Zeng, D Wu, Y Sun, Y Suo, Q Yu, M Zeng, Q Gao… - Scientific reports, 2021 - nature.com
NLRP3 inflammasome is a vital player in macrophages pyroptosis, which is a type of
proinflammatory cell-death and takes part in the pathogenesis of atherosclerosis. In this …
proinflammatory cell-death and takes part in the pathogenesis of atherosclerosis. In this …
Mechanisms of benefits of sodium-glucose cotransporter 2 inhibitors in heart failure with preserved ejection fraction
AK Pandey, DL Bhatt, A Pandey, N Marx… - European heart …, 2023 - academic.oup.com
For decades, heart failure with preserved ejection fraction (HFpEF) proved an elusive entity
to treat. Sodium-glucose cotransporter 2 (SGLT2) inhibitors have recently been shown to …
to treat. Sodium-glucose cotransporter 2 (SGLT2) inhibitors have recently been shown to …
Calycosin Alleviates Doxorubicin‐Induced Cardiotoxicity and Pyroptosis by Inhibiting NLRP3 Inflammasome Activation
L Zhang, C Fan, HC Jiao, Q Zhang… - Oxidative medicine …, 2022 - Wiley Online Library
Calycosin (CAL) is the main active component present in Astragalus and reportedly
possesses diverse pharmacological properties. However, the cardioprotective effect and …
possesses diverse pharmacological properties. However, the cardioprotective effect and …
Targeting the residual cardiovascular risk by specific anti-inflammatory interventions as a therapeutic strategy in atherosclerosis
A Hafiane, SS Daskalopoulou - Pharmacological Research, 2022 - Elsevier
Chronic subclinical inflammation is a key process in the pathogenesis of atherosclerotic
cardiovascular disease (ASCVD). Along with lipids, inflammation is essential for the initiation …
cardiovascular disease (ASCVD). Along with lipids, inflammation is essential for the initiation …
Portrayal of NLRP3 inflammasome in atherosclerosis: current knowledge and therapeutic targets
We are witnessing the globalization of a specific type of arteriosclerosis with rising
prevalence, incidence and an overall cardiovascular disease burden. Currently …
prevalence, incidence and an overall cardiovascular disease burden. Currently …
Effects of ketogenic diet on muscle metabolism in health and disease
EI Yakupova, AD Bocharnikov, EY Plotnikov - Nutrients, 2022 - mdpi.com
Dietary intervention is widely used as a therapeutic approach ranging from the treatment of
neurological disorders to attempts to extend lifespan. The most important effect of various …
neurological disorders to attempts to extend lifespan. The most important effect of various …
Potential roles of inflammasomes in the pathophysiology of Psoriasis: A comprehensive review
Psoriasis is an inflammatory skin disease whose pathophysiology is attributed to both innate
and adaptive immune cells and molecules. Despite the crucial roles of the immune system in …
and adaptive immune cells and molecules. Despite the crucial roles of the immune system in …
Vascular stress signaling in hypertension
SM Cicalese, JF da Silva, F Priviero, RC Webb… - Circulation …, 2021 - Am Heart Assoc
Cells respond to stress by activating a variety of defense signaling pathways, including cell
survival and cell death pathways. Although cell survival signaling helps the cell to recover …
survival and cell death pathways. Although cell survival signaling helps the cell to recover …