An epigenetic role of mitochondria in cancer
Mitochondria are not only the main energy supplier but are also the cell metabolic center
regulating multiple key metaborates that play pivotal roles in epigenetics regulation. These …
regulating multiple key metaborates that play pivotal roles in epigenetics regulation. These …
Targeting mitochondrial impairment in Parkinson's disease: challenges and opportunities
The underlying pathophysiology of Parkinson's disease is complex, but mitochondrial
dysfunction has an established and prominent role. This is supported by an already large …
dysfunction has an established and prominent role. This is supported by an already large …
[HTML][HTML] Non-invasive photobiomodulation treatment in an Alzheimer Disease-like transgenic rat model
L Yang, C Wu, E Parker, Y Li, Y Dong, L Tucker… - Theranostics, 2022 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) is the most common form of dementia in the elderly, causing
neuronal degeneration and cognitive deficits that significantly impair independence and …
neuronal degeneration and cognitive deficits that significantly impair independence and …
Long-term exercise pre-training attenuates Alzheimer's disease–related pathology in a transgenic rat model of Alzheimer's disease
L Yang, C Wu, Y Li, Y Dong, CYC Wu, RHC Lee… - Geroscience, 2022 - Springer
Alzheimer's disease (AD) is the most common form of dementia. Despite enormous efforts
around the world, there remains no effective cure for AD. This study was performed to …
around the world, there remains no effective cure for AD. This study was performed to …
Insulin resistance at the crossroad of Alzheimer disease pathology: A review
J Berlanga-Acosta, G Guillén-Nieto… - Frontiers in …, 2020 - frontiersin.org
Insulin plays a major neuroprotective and trophic function for cerebral cell population, thus
countering apoptosis, beta-amyloid toxicity, and oxidative stress; favoring neuronal survival; …
countering apoptosis, beta-amyloid toxicity, and oxidative stress; favoring neuronal survival; …
[HTML][HTML] High-intensity interval training ameliorates Alzheimer's disease-like pathology by regulating astrocyte phenotype-associated AQP4 polarization
S Feng, C Wu, P Zou, Q Deng, Z Chen, M Li, L Zhu… - Theranostics, 2023 - ncbi.nlm.nih.gov
Background: Alzheimer's disease (AD), one of the most common forms of dementia, is a
widely studied neurodegenerative disease characterized by Aβ accumulation and tau …
widely studied neurodegenerative disease characterized by Aβ accumulation and tau …
Oxidative stress and mitochondrial dysfunction following traumatic brain injury: From mechanistic view to targeted therapeutic opportunities
Traumatic brain injury (TBI) is one of the most prevalent causes of permanent physical and
cognitive disabilities. TBI pathology results from primary insults and a multi‐mechanistic …
cognitive disabilities. TBI pathology results from primary insults and a multi‐mechanistic …
Hypoxia-inducible factor (HIF) in ischemic stroke and neurodegenerative disease
EV Mitroshina, MO Savyuk, E Ponimaskin… - Frontiers in cell and …, 2021 - frontiersin.org
Hypoxia is one of the most common pathological conditions, which can be induced by
multiple events, including ischemic injury, trauma, inflammation, tumors, etc. The body's …
multiple events, including ischemic injury, trauma, inflammation, tumors, etc. The body's …
[HTML][HTML] Effects of prenatal photobiomodulation treatment on neonatal hypoxic ischemia in rat offspring
L Yang, Y Dong, C Wu, H Youngblood, Y Li, X Zong… - Theranostics, 2021 - ncbi.nlm.nih.gov
Neonatal hypoxic-ischemic (HI) injury is a severe complication often leading to neonatal
death and long-term neurobehavioral deficits in children. Currently, the only treatment option …
death and long-term neurobehavioral deficits in children. Currently, the only treatment option …
Molecular hydrogen: an emerging therapeutic medical gas for brain disorders
C Wu, P Zou, S Feng, L Zhu, F Li, TCY Liu, R Duan… - Molecular …, 2023 - Springer
Oxidative stress and neuroinflammation are the main physiopathological changes involved
in the initiation and progression of various neurodegenerative disorders or brain injuries …
in the initiation and progression of various neurodegenerative disorders or brain injuries …