Astrocytes are a vital cellular component of the central nervous system that impact neuronal
function in both healthy and pathological states. This includes intercellular signals to …

Long-range intercellular communication between Central Nervous System (CNS) cells is an
essential process for preserving CNS homeostasis. Paracrine signaling, extracellular …

Background: Reproducibility of human cortical organoid (hCO) phenotypes remains a
concern for modeling neurodevelopmental disorders. While guided hCO protocols …

Progress in understanding the molecular mechanisms underlying human psychiatric 7
disease has been hampered by the lack of models that can reflect the genetic states 8 …

Advances in stem cell technology enable neuroscientists to develop induced pluripotent
stem cell (iPSC)-based neuronal models of varying complexity, ranging from single human …

Multi-electrode recording of neural activity in cultures offer opportunities for understanding
how the structure of a network gives rise to function. Although it is hypothesized that network …

Dyslexia is a genetic and heritable disorder that has yet to discover the treatment of it,
especially at the molecular and drug intervention levels. This review provides an overview of …

Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by a wide
range of symptoms and varying degrees of severity. Understanding the underlying …

Advances in stem cell technology enable neuroscientists to develop induced pluripotent
stem cell (iPSC)-based neuronal models of varying complexity, ranging from single human …

PTENopathy refers to a class of uncommon genetic disorders brought on by changes or
mutations in the phosphatase and tensin homologue (PTEN) gene. A wide range of clinical …