Resveratrol and inflammatory bowel disease: The evidence so far

S Nunes, F Danesi, D Del Rio, P Silva - Nutrition research reviews, 2018 - cambridge.org
Despite the fact that inflammatory bowel disease (IBD) has still no recognised therapy,
treatments which have proven at least mildly successful in improving IBD symptoms include …

Animal models of inflammatory bowel disease

A Mizoguchi - Progress in molecular biology and translational …, 2012 - Elsevier
Inflammatory bowel disease (IBD) is a chronic intestinal inflammatory condition that is
medicated by genetic, immune, and environmental factors. At least 66 different kinds of …

Butyrate suppresses colonic inflammation through HDAC1-dependent Fas upregulation and Fas-mediated apoptosis of T cells

MA Zimmerman, N Singh, PM Martin… - American Journal …, 2012 - journals.physiology.org
Butyrate, an intestinal microbiota metabolite of dietary fiber, has been shown to exhibit
protective effects toward inflammatory diseases such as ulcerative colitis (UC) and …

[HTML][HTML] Inflammation-specific targeted carriers for local drug delivery to inflammatory bowel disease

NG Kotla, R Singh, BV Baby, S Rasala, J Rasool… - Biomaterials, 2022 - Elsevier
Delivering drugs directly to the inflamed intestinal sites to treat inflammatory bowel disease
(IBD), particularly Crohn's and ulcerative colitis, is highly challenging. Recent advances in …

[HTML][HTML] Contribution of the IL-17/IL-23 axis to the pathogenesis of inflammatory bowel disease

CS Cătană, IB Neagoe, V Cozma… - World journal of …, 2015 - ncbi.nlm.nih.gov
Inflammatory bowel diseases (IBDs) are chronic disorders of modern society, requiring
management strategies aimed at prolonging an active life and establishing the exact …

Hydrogen sulfide protects from colitis and restores intestinal microbiota biofilm and mucus production

JP Motta, KL Flannigan, TA Agbor… - Inflammatory bowel …, 2015 - academic.oup.com
Background Microbiota dysbiosis and impaired barrier function are among the most
prominent features of inflammatory bowel disease. In the gastrointestinal tract, hydrogen …

Induced and natural regulatory T cells in the development of inflammatory bowel disease

CG Mayne, CB Williams - Inflammatory bowel diseases, 2013 - academic.oup.com
The mucosal immune system mediates contact between the host and the trillions of
microbes that symbiotically colonize the gastrointestinal tract. Failure to tolerate the antigens …

Alginate/chitosan microparticles for gastric passage and intestinal release of therapeutic protein nanoparticles

K Ling, H Wu, AS Neish, JA Champion - Journal of Controlled Release, 2019 - Elsevier
Enzymes with intracellular activity have significant potential to treat diseases. Protein
nanoparticles (NPs) considerably enhance intracellular delivery of enzymes. We have …

Drug delivery to inflamed colon by nanoparticles: comparison of different strategies

R Coco, L Plapied, V Pourcelle, C Jérôme… - International journal of …, 2013 - Elsevier
For inflammatory bowel disease (IBD) treatment, local delivery of molecules loaded in
nanoparticles to the inflamed colon could be a promising strategy. The aim of this study was …

[HTML][HTML] Receptor for advanced glycation end products acts as a fuel to colorectal cancer development

F Azizian-Farsani, N Abedpoor… - Frontiers in …, 2020 - frontiersin.org
Receptor for advanced glycation end-products (RAGE) is a multiligand binding and single-
pass transmembrane protein taken in diverse chronic inflammatory conditions. RAGE …