Sepsis management in the cardiac intensive care unit

Y Zhang, MT McCurdy, J Ludmir - Journal of Cardiovascular …, 2023 - mdpi.com
Septic shock management in the cardiac intensive care unit (CICU) is challenging due to the
complex interaction of pathophysiology between vasodilatory and cardiogenic shock …

Recent trends and challenges to overcome Pseudomonas aeruginosa infections

A Ammazzalorso, A Granese… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Pseudomonas aeruginosa (PA) is a Gram-negative bacterium that can cause a
wide range of severe infections in immunocompromised patients. The most difficult …

Association between combination antibiotic therapy as opposed as monotherapy and outcomes of ICU patients with Pseudomonas aeruginosa ventilator-associated …

A Foucrier, T Dessalle, S Tuffet, L Federici… - Critical Care, 2023 - Springer
Background The optimal treatment duration and the nature of regimen of antibiotics
(monotherapy or combination therapy) for Pseudomonas aeruginosa ventilator‑associated …

Community-acquired skin and soft-tissue infections in people who inject drugs

F Allaw, J Zakhour, SS Kanj - Current Opinion in Infectious …, 2023 - journals.lww.com
Community-acquired skin and soft-tissue infections in people... : Current Opinion in Infectious
Diseases Community-acquired skin and soft-tissue infections in people who inject drugs …

A paper biosensor for overcoming matrix effects interfering with the detection of sputum pyocyanin with competitive immunoassays

C Adrover-Jaume, A Clemente… - Microchimica Acta, 2023 - Springer
Detecting sputum pyocyanin (PYO) with a competitive immunoassay is a promising
approach for diagnosing Pseudomonas aeruginosa respiratory infections. However, it is not …

Infective endocarditis after transcatheter aortic valve replacement: challenges in the diagnosis and management

J Zakhour, F Allaw, S Kalash, S Wehbe, SS Kanj - Pathogens, 2023 - mdpi.com
Although initially conceived for high-risk patients who are ineligible for surgical aortic valve
replacement (SAVR), transcatheter aortic valve replacement (TAVR) is now recommended …

Quercetin attenuates Pseudomonas aeruginosa-induced acute lung inflammation by inhibiting PI3K/AKT/NF-κB signaling pathway

X Jia, M Gu, J Dai, J Wang, Y Zhang, Z Pang - Inflammopharmacology, 2024 - Springer
Pseudomonas aeruginosa is an opportunistic pathogen that commonly causes infections in
immunocompromised individuals with significant morbidity and mortality. Quercetin is a …

Synergistic Effects of Gentamicin, Cefepime, and Ciprofloxacin on Biofilm of Pseudomonas aeruginosa

M Usman, A Marcus, A Fatima, B Aslam… - Infection and Drug …, 2023 - Taylor & Francis
Background Pseudomonas aeruginosa is an opportunistic pathogen involved in number of
hospital-acquired infections such as catheter-associated urinary tract infections, bacteremia …

[HTML][HTML] Unitig-centered pan-genome machine learning approach for predicting antibiotic resistance and discovering novel resistance genes in bacterial strains

DT Do, MR Yang, TNS Vo, NQK Le, YW Wu - Computational and Structural …, 2024 - Elsevier
In current genomic research, the widely used methods for predicting antimicrobial resistance
(AMR) often rely on prior knowledge of known AMR genes or reference genomes. However …

Using host-mimicking conditions and a murine cutaneous abscess model to identify synergistic antibiotic combinations effective against Pseudomonas aeruginosa

N Lyons, W Wu, Y Jin, IL Lamont… - Frontiers in Cellular and …, 2024 - frontiersin.org
Antibiotic drug combination therapy is critical for the successful treatment of infections
caused by multidrug resistant pathogens. We investigated the efficacy of β-lactam and β …