Because nonopioid analgesics are much sought after, we computationally docked more
than 301 million virtual molecules against a validated pain target, the α2A-adrenergic …

Breast cancer is the most common and deadliest type of cancer in women. Stress exposure
has been associated with carcinogenesis and the stress released neurotransmitters …

Exercise, psychosocial stress, and drugs such as adrenergic agonists and antagonists
increase the concentrations of catecholamines and/or alter adrenergic signaling …

Purpose The sympathetic nervous system drives breast cancer progression through β-
adrenergic receptor signalling. This discovery has led to the consideration of cardiac β …

Catecholamine‐triggered β‐adrenoceptor (β‐AR) signaling is essential for the correct
functioning of the heart. Although both β1‐and β2‐AR subtypes are expressed in …

Physiologically, β-adrenoceptors are major regulators of lipid metabolism, which may be
reflected in alterations in lipid droplet dynamics. β-adrenoceptors have also been shown to …

Adrenaline, which participates in the neuroendocrine response that occurs during stress and
perimenopause, may be tumorigenic. This exploratory study aimed at investigating whether …

Inhaled long-acting β-adrenergic agonists (LABAs) and short-acting β-adrenergic agonists
are approved for the treatment of obstructive lung disease via actions mediated by β 2 …

G protein activation represents an early key event in the complex GPCR signal transduction
process and is usually studied by label-dependent methods targeting specific molecular …

Adrenoceptors are G protein-coupled receptors involved in a large variety of physiological
processes, also under pathological conditions. This is due in large part to their ubiquitous …