Epigenetics of stress, addiction, and resilience: therapeutic implications

JL Cadet - Molecular neurobiology, 2016 - Springer
Substance use disorders (SUDs) are highly prevalent. SUDs involve vicious cycles of binges
followed by occasional periods of abstinence with recurrent relapses despite treatment and …

[HTML][HTML] DNA modifications: function and applications in normal and disease States

VRB Liyanage, JS Jarmasz, N Murugeshan… - Biology, 2014 - mdpi.com
Epigenetics refers to a variety of processes that have heritable effects on gene expression
programs without changes in DNA sequence. Key players in epigenetic control are chemical …

Hippocampal structural and functional changes associated with electroconvulsive therapy response

CC Abbott, T Jones, NT Lemke, P Gallegos… - Translational …, 2014 - nature.com
Previous animal models and structural imaging investigations have linked hippocampal
neuroplasticity to electroconvulsive therapy (ECT) response, but the relationship between …

Glycerophosphate/acylglycerophosphate acyltransferases

A Yamashita, Y Hayashi, N Matsumoto… - Biology, 2014 - mdpi.com
Acyl-CoA: glycerol-3-phosphate acyltransferase (GPAT) and acyl-CoA: 1-acyl-glycerol-3-
phosphate acyltransferase (AGPAT) are involved in the de novo synthesis of triacylglycerol …

[HTML][HTML] Epigenetic modification impacting brain functions: Effects of physical activity, micronutrients, caffeine, toxins, and addictive substances

R Mallick, AK Duttaroy - Neurochemistry International, 2023 - Elsevier
Abstract Changes in gene expression are involved in many brain functions. Epigenetic
processes modulate gene expression by histone modification and DNA methylation or RNA …

TET1 is a beige adipocyte-selective epigenetic suppressor of thermogenesis

S Damal Villivalam, D You, J Kim, HW Lim… - Nature …, 2020 - nature.com
It has been suggested that beige fat thermogenesis is tightly controlled by epigenetic
regulators that sense environmental cues such as temperature. Here, we report that …

Epigenetic landscape of amphetamine and methamphetamine addiction in rodents

A Godino, S Jayanthi, JL Cadet - Epigenetics, 2015 - Taylor & Francis
Amphetamine and methamphetamine addiction is described by specific behavioral
alterations, suggesting long-lasting changes in gene and protein expression within specific …

Developmental and behavioral consequences of prenatal methamphetamine exposure: A review of the Infant Development, Environment, and Lifestyle (IDEAL) study

LM Smith, S Diaz, LL LaGasse, T Wouldes… - Neurotoxicology and …, 2015 - Elsevier
This study reviews the findings from the Infant Development, Environment, and Lifestyle
(IDEAL) study, a multisite, longitudinal, prospective study designed to determine maternal …

[HTML][HTML] Chromatin-mediated alternative splicing regulates cocaine-reward behavior

SJ Xu, SI Lombroso, DK Fischer, MD Carpenter… - Neuron, 2021 - cell.com
Neuronal alternative splicing is a key gene regulatory mechanism in the brain. However, the
spliceosome machinery is insufficient to fully specify splicing complexity. In considering the …

An update on the epigenetics of psychotic diseases and autism

HM Abdolmaleky, JR Zhou, S Thiagalingam - Epigenomics, 2015 - Taylor & Francis
The examination of potential roles of epigenetic alterations in the pathogenesis of psychotic
diseases have become an essential alternative in recent years as genetic studies alone are …