Successful aerosol therapy generally depends on the small percentage (typically 10
percent) of the drug dose delivered to the lungs from metered-dose inhalers (MDIs) …

The combination of heart failure and chronic obstructive pulmonary disease presents many
therapeutic challenges. The cornerstones of therapy are beta-blockers and beta-agonists …

Objective.—To maximize deposition of an aerosolized dose of insulin (mean±SD=
0.99±0.06 U/kg of body weight) in the lungs of subjects with non—insulin-dependent …

A radioaerosol technique has been developed in order to assess deposition patterns from a
new metered dose powder inhaler (Turbuhaler, Astra Pharmaceuticals). The radionuclide …

The fractional deposition from an Inspiron 'Mini-Neb'jet nebulizer was assessed in six
normal and two asthmatic subjects using technetium-99m-labelled milli-microspheres of …

The goals of these experiments were to efficiently deliver aerosolized adeno-associated
virus (AAV) vector to the lungs of Rhesus macaques and to measure gene transfer and …

A new medical aerosol inhaler comprising a pressurized canister or metered dose inhaler
(MDI), an aerosol holding chamber and a one-way valve system has been designed …

Because of the pain, inconvenience, and disruption of lifestyle associated with the injection
of insulin, many patients with diabetes are noncompliant in terms of treatment regimens that …

Nebulised solutions of beta2-adrenergic stimulants are very effective in the treatment of
airflow obstruction in patients with asthma, chronic bronchitis, and emphysema1 2 and are …

The bronchodilatation achieved by the beta 2 agonist terbutaline sulphate given as
nebulised aerosol from different devices has been measured in seven patients with mild …