Connexins: a connection with the skin

G Richard - Experimental Dermatology: Review Article, 2000 - Wiley Online Library
The intercellular signaling system mediated by connexin channels is crucial for maintaining
tissue homeostasis, growth control, development, and synchronized response of cells to …

Gap junctional signaling in pattern regulation: physiological network connectivity instructs growth and form

J Mathews, M Levin - Developmental neurobiology, 2017 - Wiley Online Library
Gap junctions (GJs) are aqueous channels that allow cells to communicate via physiological
signals directly. The role of gap junctional connectivity in determining single‐cell functions …

[HTML][HTML] Characterization of innexin gene expression and functional roles of gap-junctional communication in planarian regeneration

T Nogi, M Levin - Developmental biology, 2005 - Elsevier
Planaria possess remarkable powers of regeneration. After bisection, one blastema
regenerates a head, while the other forms a tail. The ability of previously-adjacent cells to …

Connexins: sensors and regulators of cell cycling

M Vinken, E Decrock, E De Vuyst, R Ponsaerts… - … et Biophysica Acta (BBA …, 2011 - Elsevier
It is nowadays well established that gap junctions are critical gatekeepers of cell
proliferation, by controlling the intercellular exchange of essential growth regulators. In …

Connexins and apoptotic transformation

A Kalvelyte, A Imbrasaite, A Bukauskiene… - Biochemical …, 2003 - Elsevier
We examined the influence of connexin (Cx) expression on the development of apoptosis in
HeLa parental cells (coupling deficient cell line) and HeLa cells expressing wild-type Cx43 …

Connexin 26 and basic fibroblast growth factor are expressed primarily in the subpial and subependymal layers in adult brain parenchyma: roles in stem cell …

F Mercier, GI Hatton - Journal of Comparative Neurology, 2001 - Wiley Online Library
The gap junction protein connexin 26 (Cx26) has been detected previously in the
parenchyma of the developing brain and in the developing and adult meninges, but there is …

Reduction of malignant phenotype of HEPG2 cell is associated with the expression of connexin 26 but not connexin 32

T Yano, FJ Hernandez-Blazquez, Y Omori… - …, 2001 - academic.oup.com
Connexin (Cx) genes have a negative growth effect on tumour cells with certain specificity.
However, it is not clear whether each Cx gene can act similarly in growth control …

Cadmium decreases gap junctional intercellular communication in mouse liver

SH Jeong, SSM Habeebu… - Toxicological Sciences, 2000 - academic.oup.com
Cadmium (Cd) is an environmental pollutant of increasing importance, due to
industrialization, smoking, and the lack of effective therapy for Cd poisoning. The general …

Regulation of Sertoli cell and germ cell differentiation

R Brehm, K Steger - 2005 - books.google.com
Unwanted childlessness affects approximately one in six couples worldwide.-though the
exact proportion of the predominant cause of the problem remains controversial, according …

[HTML][HTML] Pan-cancer analysis of the prognostic and immunological role of GJB2: A potential target for survival and immunotherapy

Y Jia, B Guo, W Zhang, F Wang, Y Zhang… - Frontiers in …, 2023 - frontiersin.org
Background GJB2 plays an essential role in the growth and progression of several cancers.
However, asystematic pan-cancer analysis of GJB2 is lacking. Therefore, in this study, we …