How I treat disseminated intravascular coagulation

M Levi, M Scully - Blood, The Journal of the American Society …, 2018 - ashpublications.org
Disseminated intravascular coagulation (DIC) is a condition characterized by systemic
activation of coagulation, potentially leading to thrombotic obstruction of small and midsize …

DIC in pregnancy–pathophysiology, clinical characteristics, diagnostic scores, and treatments

O Erez, M Othman, A Rabinovich, E Leron… - Journal of blood …, 2022 - Taylor & Francis
Obstetrical hemorrhage and especially DIC (disseminated intravascular coagulation) is a
leading cause for maternal mortality across the globe, often secondary to underlying …

Viscoelastometric-guided early fibrinogen concentrate replacement during postpartum haemorrhage: OBS2, a double-blind randomized controlled trial

PW Collins, R Cannings-John… - BJA: British Journal …, 2017 - academic.oup.com
Background: Postpartum haemorrhage (PPH) can be exacerbated by haemostatic failure.
We hypothesized that early fibrinogen replacement, guided by viscoelastometric testing …

Haemostatic management of obstetric haemorrhage

RE Collis, PW Collins - Anaesthesia, 2015 - Wiley Online Library
The haemostatic management of major obstetric haemorrhage remains challenging, and
current published guidance relies heavily on experience from the non‐pregnant population …

Disseminated intravascular coagulation: an update on pathogenesis and diagnosis

M Levi, S Sivapalaratnam - Expert review of hematology, 2018 - Taylor & Francis
Introduction: Activation of the hemostatic system can occur in many clinical conditions.
However, a systemic and strong activation of coagulation complicating clinical settings such …

Disseminated intravascular coagulation in pregnancy: insights in pathophysiology, diagnosis and management

O Erez, SA Mastrolia, J Thachil - American journal of obstetrics and …, 2015 - Elsevier
Disseminated intravascular coagulation (DIC) is a life-threatening situation that can arise
from a variety of obstetrical and nonobstetrical causes. Obstetrical DIC has been associated …

[HTML][HTML] Oxidative stress in preeclampsia and the role of free fetal hemoglobin

SR Hansson, Å Nääv, L Erlandsson - Frontiers in physiology, 2015 - frontiersin.org
Preeclampsia is a leading cause of pregnancy complications and affects 3–7% of pregnant
women. This review summarizes the current knowledge of a new potential etiology of the …

Pathogenesis and diagnosis of disseminated intravascular coagulation

M Levi - International journal of laboratory hematology, 2018 - Wiley Online Library
Several clinical conditions, in particular those associated with a systemic inflammatory
response, can cause some degree of activation of coagulation but when the procoagulant …

Standard haemostatic tests following major obstetric haemorrhage

L De Lloyd, R Bovington, A Kaye, RE Collis… - International journal of …, 2011 - Elsevier
BACKGROUND: Postpartum haemorrhage is an important cause of maternal morbidity and
mortality. It is associated with haemostatic impairment which may exacerbate bleeding …

[HTML][HTML] Haemostatic support in postpartum haemorrhage: A review of the literature and expert opinion

S Hofer, J Blaha, PW Collins… - European Journal of …, 2023 - journals.lww.com
Postpartum haemorrhage (PPH) remains the leading cause of pregnancy-related deaths
worldwide. Typically, bleeding is controlled by timely obstetric measures in parallel with …