Oligodendrocyte precursor cells (OPCs) are a population of tissue-resident glial cells found
throughout the CNS, constituting approximately 5% of all CNS cells and persisting from …

Axonal regeneration and functional recovery are poor after spinal cord injury (SCI), typified
by the formation of an injury scar. While this scar was traditionally believed to be primarily …

The treatment of spinal cord injury (SCI) remains unsatisfactory owing to the complex
pathophysiological microenvironments at the injury site and the limited regenerative …

Background Spinal cord injury (SCI) causes neural disconnection and persistent
neurological deficits, so axon sprouting and plasticity might promote recovery. Soluble Nogo …

Restoring function in chronic stages of spinal cord injury (SCI) has often been met with
failure or reduced efficacy when regenerative strategies are delayed past the acute or sub …

Despite substantial progress in understanding the biology of axon regeneration in the CNS,
our ability to promote regeneration of the clinically important corticospinal tract (CST) after …

Neonatal spinal cord tissues exhibit remarkable regenerative capabilities as compared to
adult spinal cord tissues after injury, but the role of extracellular matrix (ECM) in this process …

Spinal cord injury (SCI) is a severe neurological injury caused by traffic accidents, trauma, or
falls, which leads to significant loss of sensory, motor, and autonomous functions and …

Introduction Spinal cord injury (SCI) is a central nervous system injury that is primarily
traumatic and manifests as autonomic dysfunction below the level of injury. Our previous …

Riluzole is commonly used as a neuroprotective agent for treating traumatic spinal cord
injury (SCI), which works by blocking the influx of sodium and calcium ions and reducing …